Researcher
Research Scientist, Predictive Sciences (Reverse Translation) Full-time
CITRE, based in Seville, Spain, is Bristol-Myers Squibb’s research institute in Europe, and link to the European research community. Informatics & Predictive Sciences at CITRE performs innovative computational research to inform decisions across all stages of drug development. Areas of research include computational and network biology, machine/deep learning, cheminformatics, predictive modeling, patient stratification, and method development for analysis and interpretation of biological and real-world data. In close collaboration with our in-house laboratory, we look to set a new standard in rational design of novel targeted therapies for well-defined patient segments.
We are looking for an enthusiastic, creative and collaborative Research Scientist, Predictive Sciences (Reverse Translation) to join a multi-disciplinary team to:
Develop and apply computational methods for in-depth analysis of stratified patient data to gain mechanistic insight into driver mechanisms
Collaborate with disease stratification and target identification teams to leverage stratification results to impact discovery of novel therapies
Perform integrative analysis to derive validation-ready target hypotheses, linked to clearly defined patient subtypes
Contribute to the identification of suitable in-vitro models and validation scenarios
Collaborate experimental teams on iterative validation of therapeutic and mechanistic hypotheses
Requirements:
PhD in a relevant discipline, accompanied by original research publications.
Expertise in scripting/programming (e.g. R, Matlab, Python or others) and relevant libraries and software (e.g. Bioconductor).
Experience analyzing high-throughput biological data, e.g. RNA-seq, WGS/WES, ChIP-seq, proteomics, etc
Experience with high-performance computing, including cloud computing, would be advantageous
Attention to detail and capacity to communicate technical/scientific concepts clearly and concisely to audiences of varied backgrounds.
Verbal and written English language fluency.
Please, attach a cover letter with your motivation for applying to this role, this would be highly appreciated in order to consider your profile for this opportunity.
The position advertised is fixed-term (24 months) and based in Seville, Spain. These positions present a unique opportunity to experience research in an industry setting and to contribute to helping patients with unmet medical need, while performing cutting-edge research and maintaining close ties to academia.