The Anastassiou Laboratory studies how the molecular and cellular composition of neurons translates to their phenotype and how these properties combine in brain circuits to produce function or, in the case of disease, dysfunction.
The Anastassiou Lab has a broad background in multimodal cellular data (electrophysiology, anatomy, transcriptomics) and the development of state-of-the-art computational workflows (statistical learning, optimization and simulation) to understand cellular activity in behavior and disease. Uniquely, this work includes human brain tissue, both as a byproduct from surgery as well as from model systems such as human pluripotent stem cells. The Anastassiou Lab successfully pursues collaborations with clinicians to translate cellular and circuit findings to gain a better understanding of diseases such as epilepsy and Parkinson’s disease, as well as development of improved therapies.
To learn more about Dr. Anastassiou’s research, please visit: Anastassiou Research Lab | Cedars-Sinai . For questions and inquiries, reach out to email@example.com
Are you ready to be a part of breakthrough research?
The Anastassiou team employs multi-modal single-cell investigations in human circuits to understand cortical function and dysfunction as occurring in diseases like epilepsy. Working independently but in close cooperation and in consultation on the team of Costas Anastassiou, PhD, in the Department of Neurosurgery, the Postdoctoral Scientist will design and perform whole-cell patch-clamp experiments to investigate human live or/and human-derived single neurons. Experience in whole-cell patch-clamping and related data analyses is a must. Experience in techniques such as patch-seq is considered advantageous.
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Tagged as: Life Sciences
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