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Postdoctoral Fellow
Post-doctoral researcher in the cell biology of pigment organelles Full-time
The Marks laboratory seeks self-motivated post-doctoral applicants to join the lab’s NIH-funded efforts on the biogenesis of melanosomes, the pigment-producing subcellular organelles in skin and ocular melanocytes. Our lab at the Children’s Hospital of Philadelphia Research Institute and the University of Pennsylvania employs cellular models of rare genetic diseases and collaborative efforts with mouse and human geneticists to dissect vesicular trafficking processes and transmembrane transporter function during the maturation of melanosomes and other cell type-specific organelles using cell biological, biochemical, and genetic approaches (see https://www.med.upenn.edu/markslab/). Available funded projects include mechanisms of organellar pH control by the products of oculocutaneous albinism genes and their interactors and functional dissection of the products of novel human pigmentation genes. We also have dormant projects on the assembly of the functional amyloid protein, PMEL, and on protein sorting to lysosome-related organelles in megakaryocytes and platelets. Successful applicants will have a Ph.D. in cell/ molecular biology or related fields and a strong background in cell biology, molecular biology, protein biochemistry, cellular physiology, and/or cutting-edge microscopy.
The Children’s Hospital of Philadelphia Research Institute (CHOP) is highly integrated with the Perelman School of Medicine at the University of Pennsylvania (Penn). Both institutions share the same campus, and all core facilities, seminars, collaborative opportunities, and other intellectual endeavors are shared. The Children’s Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, sexual orientation, age, religion, national or ethnic origin, disability or veteran status.
Interested applicants should send a cover letter, CV, and the names of three referees to me at marksm@pennmedicine.upenn.edu.
Michael S. (Mickey) Marks, Ph.D.
Professor, Dept. of Pathology & Laboratory Medicine and Dept. of Physiology
Children’s Hospital of Philadelphia and
University of Pennsylvania Perelman School of Medicine