Postdoctoral Fellow
Postdoctoral Research Scientist – Next-Generation Biomolecular Profiling – Columbia University Full-time
Departments of Biological Sciences and Chemistry, Columbia University
The Bussemaker and Shah labs at Columbia University are looking for outstanding applicants for a joint postdoctoral position. The goal is to develop the next generation of methods for probing biomolecular interactions, using a combination of protein display technologies, deep sequencing, and advanced machine learning methods. This project is funded in part by a pilot award from Columbia University’s Translational Therapeutics Accelerator Program.
The successful candidate is expected to lead the development of cutting-edge experimental methods, while working closely with a highly interdisciplinary team of physicists, engineers, biochemists and computational biologists to realize this goal.
The Bussemaker Lab has pioneered biophysically interpretable computational methods for defining the DNA binding specificity of transcription factors and the structure and function of gene regulatory networks based on integrative analysis of various types of functional genomics data. The Shah Lab uses chemical and biological approaches, including deep sequencing-based high-throughput biochemical assays, to probe the structures and functions of eukaryotic signaling enzymes, with particular focus on protein tyrosine kinases and phosphatases.
Required Skills
The ideal candidate will have a Ph.D. and a strong experimental background in chemical biology, biochemistry, and/or molecular biology, preferably with experience implementing protein display methods (e.g. bacterial, yeast, phage, or mRNA display). The candidate must have an excellent research track record and a proven ability to develop new experimental assays/technologies. In addition, they should have a strong interest in biological applications, translational research, and/or technology development. Experience developing microfluidic applications and/or in the biotech industry is a plus but not required.
How to Apply
Please make sure to include: (i) cover letter describing your research interests and goals; (ii) CV with full publication list (please highlight relevant papers); (iii) contact information for at least three references. You can send your applications to hjb2004@columbia.edu and neel.shah@columbia.edu. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.