PhD Student
PhD Student in Pharmaceutical Science with a focus on automated phenotypic drug profiling Full-time
We are currently looking for an ambitious and highly motivated PhD student with a good background in cell biology as well as interest in molecular biology, high-throughput screening and bioinformatics, to join the research group of Prof. Ola Spjuth (group website: https://pharmb.io). The position includes both laboratory experiments using our robotized cell profiling laboratory, and data analysis of primarily images from high-content imaging of cells. The successful candidate will join an active and interdisciplinary team of researchers, and participate in a project to build up an intelligent, automated laboratory for cell profiling, with applications in precision cancer medicine.
Qualifications:
The highly motivated candidate should have a MSc in cell/molecular biology/biotechnology or equivalent field and previous laboratory experience. Familiarity with standard lab techniques is required, including:
- Cell culture of cancer cells and other cellular models, including primary cells
- Molecular biology, including among others western blotting, CRISPR/Cas9, cloning, siRNA and DNA transfections, RNA/DNA extraction, PCR and quantitative real-time PCR techniques
- Cell viability, proliferation and apoptosis assays.
- Immunofluorescence staining and immunoprecipitation techniques.
- Fluorescence-activated cell sorting (FACS)
- Liquid handling and automation Fluorescent microscopy imaging
Experience with data analysis and image analysis is meriting, and the candidate should be highly interested to learn/deepen the competence to automate lab operations with robotics and scripting. The candidate should have excellent communication skills and be keen on actively interacting with other team members including biologists, software engineers, and researchers in AI/ML. Excellent skills in oral and written English are required, as well as the ability to work both independently and as part of a highly interdisciplinary team.
More information about the position: https://pharmb.io/blog/open-positions-precision-cancer-medicine-2021/