We are seeking a highly motivated and enthusiastic Postdoctoral Researcher to join the group of Dr. Mikayel AZNAURYAN at the European Institute of Chemistry and Biology (IECB), University of Bordeaux, France (http://www.aznauryan-lab.com/). The position is fixed term for 1 year, with a possibility of further extension. Possible starting date is from January 2021.
The host group
We are interested in studies of interactions between intrinsically disordered proteins (IDPs) and nucleic acids, with particular focus on disordered translation initiation factors and understanding the molecular mechanisms through which these IDPs participate in the regulation of mRNA translation. For this we use a bouquet of state-of-the-art techniques, among which the central role is attributed to single-molecule FRET (Aznauryan et al. PNAS 2016, Aznauryan et al. JACS 2013, Aznauryan et al. NAR 2016), both in vitro and in live cells (König et al. Nature methods 2015).
The successful applicant will be part of our multidisciplinary research team to utilize single-molecule FRET spectroscopy to study conformational dynamics of intrinsically disordered translation initiation factors with then aim of understanding the mechanisms of their function in the context of translation initiation. The project will involve design and preparation of protein systems (expression, purification, fluorescent labeling) and designing and carrying out single-molecule spectroscopy experiments, progressively from in vitro towards in-cell.
The potential candidate
For more information regarding a career at University of Bordeaux and IECB please visit:
Interested applicants should send a cover letter describing their previous achievements and experience and a CV (with contact information for at least two references) to Dr. Mikayel AZNAURYAN (firstname.lastname@example.org).
Tagged as: Life Sciences, Physics
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