Who are we?
The Laboratory of Imagenomics at the Genome Institute of Singapore, A*STAR is a group of researchers interested in developing and applying a new kind of “in situ omics” technology for spatially resolved systems biology. We use state-of-the-art microscopy, fluidics, and next-generation sequencing, combined with cutting edge computational tools to analyse genomics, transcriptomics, and other information of single cells from and within complex tissues. This “in situ omics” data can reveal molecularly defined cell types, gene networks, as well as cellular signalling events within their spatial context, all of which are critical for understanding tissue biology and disease mechanisms.
What is the job about?
We are looking for a Research Officer to work on advanced imaging methods for 3D spatial transcriptomics. We will build and develop integrated instruments (microscopes+fluidics) to perform deep fluorescence imaging into thick tissue or whole organs. This project will include optical engineering where we will make and improve new or existing microscopes (lightsheet or spinning disk confocal) and image analysis where we will design and write custom algorithms to process and interpret the 3D image data that we will acquire. The overarching goal is to generate new 3D spatial maps of gene expression of 100s to 1000s of genes in single cells in thick tissues and whole organs.
Genome Institute of Singapore, A*STAR
On-the-job training will be provided by other members of the team.
If you’re interested in this job, please send an email with your resume or CV to Maurice (firstname.lastname@example.org).
Tagged as: Chemistry, Engineering, Life Sciences, Physics