The Wei lab at the German Cancer Research Center (DKFZ), Heidelberg, Germany, is seeking a postdoctoral fellow to work on a European Research Council-funded project addressing the source of neuronal genomic mosaicism in the brain. The Wei lab studies the genome integrity of neuronal precursor cells. Our missions are to elucidate the source of recurrent genomic alterations that contribute to brain diseases, such as cancer and neuropsychiatric disorder, and explore when and how the neuronal cells diversify their genomes.
Our group utilizes state-of-the-art technologies to understand (1) the molecular mechanism of DNA lesions in the neural stem and progenitor cells, (2) characterizing the landscape of genomic damage in the developing brain, and (3) addressing the fate of neural stem cells under genotoxic stress. Approaches, including high-throughput sequencing, omics data analyses, stem cell culture, mouse models, single-cell transcriptomics, and mathematical modeling, will be applied to this project.
The postdoc researcher will join a collaborative, energized, and collegial group. The postdoctoral recruit will work with the principle investigator closely to develop an independent project in a supportive environment. The DKFZ is the largest biomedical research institute in Germany. Together with the University of Heidelberg, the National Center for Tumor Diseases (NCT) and German Consortium of Translational Cancer Research (DKTK), the DKFZ provides an outstanding research environment that fully matches my scientific interests. Key core facilities supporting genomics, proteomics, cytometry, microscopy, and preclinical animal center have been established at the DKFZ to support the diverse research activities within the campus. The center also provides opportunities such as career round table discussion, grant writing training, and other activities to promote advanced career development.
· PhD in cellular and molecular biology, genetics, neuroscience or a related field
· Prior experience in animal model, DNA damage, embryonic neurogenesis or cell-fate mapping are preferred.
· Excellent English written and verbal communication skills
· An outstanding scientific record
· Ability to develop an independent project within the lab
Please submit the following material to Dr. Pei-Chi Wei (firstname.lastname@example.org)
1. A motivation letter,
2. Curriculum vitae including your past working/research experiences/activities in a chronological way
3. Ph.D. thesis abstract , and
4. Contact information of two referees
This project is fully funded for five years.
Tagged as: Life Sciences
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