A postdoctoral position funded by a federal grant is available in the internationally recognized cancer biology laboratory of Dr. Kenneth P. Nephew, Jerry W. and Peggy S. Throgmartin Chair in Oncology, at the Indiana University School of Medicine – Bloomington (https://nephewlab-iu.mystrikingly.com/). This project focuses on DNA damage repair and epigenetic alterations in ovarian cancer and the role DNA methylation and histone modifications in chemotherapy resistance and disease relapse. This study is a joint project with the nationally recognized cancer epigenetics laboratory of Dr. Heather O’Hagan (https://ohaganlab-iu.mystrikingly.com/). In this context, projects pursued by the successful applicants will utilize a variety of gene-specific and next generation sequencing techniques, including single-cell sequencing technology, to understand the molecular mechanism of drug resistance in ovarian cancer progenitor/stem cells in vitro and in vivo.
The laboratories are located in Bloomington, providing both a dynamic environment with interactions and core resources on the flagship campus (http://www.iub.edu/) as well as the energy and excitement of being on a major college campus. Moreover, full access to the resources available at the IU Simon Comprehensive Cancer Center (http://www.cancer.iu.edu/) and the IU School of Medicine (http://medicine.iu.edu/) are readily available.
Bloomington itself is a vibrant city with many urban amenities, including theatre productions, live music, art exhibits and a wide range of culinary options, while still being in the hilly, forested landscape of south-central Indiana (http://www.visitbloomington.com/).
A PhD degree in Molecular Biology, Biochemistry, Cellular Biology, Genomics, or a related field, a strong publication record and a shared passion for cancer research are required. A background and interest in epigenetics, chromatin biology, DNA damage repair, and/or state-of-the-science genomics (e.g., RNA-seq, ChIP-seq, ATAC-seq) will be important considerations, as will experience with rodent models of tumorigenesis and flow cytometry. The successful candidate will be expected to work independently on projects, generate and analyze data, help graduate students, and write manuscripts and grants. A competitive starting salary is commensurate with experience plus outstanding university benefits.
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Applicants should apply at the following link
Review of applications will commence immediately and will continue until the position is filled.
Tagged as: Life Sciences
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