Research Assistant
Research Assistant (with possibility to obtain PhD) in Neuroscience Full-time
++ The Cortical Plasticity group at the Neurocentre Magendie (Bordeaux, France) is seeking to recruit a Master-level research assistant (French grade: Ingenieur d’Etude) to join their group in 2021. ++ We are interested in the function of neocortical circuits and their pathophysiological modification in autism spectrum disorders (ASD). In this project we study and attempt to correct alterations in these neocortical circuits in mouse and human ASD models. ++ The project is fully funded for up to four years and the successful candidate will also have the possibility to validate their professional experience by obtaining a PhD. ++ We are looking for a highly motivated and proactive team player with experience in the culture of human derived neurons from iPSCs and CRISPR/Cas9 gene editing. Experience in animal experimentation, in particular behavioral tasks, would be a plus. The appointee must have a Masters level degree or equivalent. The candidate should also have a good level of proficiency in English. ++ The team is a member of the Bordeaux Neurocampus — a center of excellence for neuroscience research in France. The day-to-day language is English, but support would be provided for learning French if the candidate so wishes. ++ Projected start date — March/April 2021. ++ Interested applicants should send a cv, brief statement of research experience and interests, and names of 2-3 references to Dr. Andreas Frick: andreas.frick@inserm.fr. ++ A few project-relevant publications from our team: – Möhrle, D, et al. (2020) What we learn from a genetic rodent model about autism. Neurosci Biobehav Rev. 2019 Dec 27;109:29-53. – Aloisi, E., et al. & Frick, A. (2017) Nature Communications. 2017 Oct 24;8(1):1103. – Haberl, M. G., et al. & Frick A. (2015). Structural-functional connectivity deficits of neocortical circuits in the Fmr1-/y mouse model of autism. Science Advances, 1(10), e1500775–e1500775 – Zhang, Y. et al. & Frick, A. (2014) Dendritic Channelopathies Contribute to Neocortical Hyperexcitability and Sensory Hypersensitivity in the Fmr1-/y Mice. Nature Neuroscience, 17, 1701–1709 (2014) doi:10.1038/nn.3864. ++ Press (selection): – http://presse.inserm.fr/une-piste-pour-retablir-la-bonne-integration-des-informations-sensorielles-chez-les-autistes/16789/ – http://presse.inserm.fr/connexions-defaillantes-a-travers-le-cerveau-en-cause-dans-certains-troubles-de-lautisme/21521/ – https://www.inserm.fr/information-en-sante/dossiers-information/autisme – https://www.inserm.fr/information-en-sante/magazine/inserm-magazine-ndeg45 – https://www.fondation-fondamental.org/les-maladies-mentales/troubles-du-spectre-de-lautisme – https://www.spectrumnews.org/