We are seeking a highly motivated and talented postdoc to join our new group at the Department of Medical Biochemistry and Cell Biology at Sahlgrenska Academy, Gothenburg University, Sweden.
Mitochondria convert chemical energy into ATP by utilizing a system of molecular machines, the respiratory chain complexes. The complexes driving oxidative phosphorylation are a mosaic of proteins encoded by the nuclear and the mitochondrial DNA. Therefore, assembly of the respiratory chain and the ATPase requires not only expression and import of many nuclear encoded proteins but also synthesis of mitochondrially encoded proteins. The mitochondrial genetic system is responsible for replication and transcription of the mitochondrial genome and for the synthesis of a few polypeptides by organelle-specific ribosomes. Dysfunction of these processes underlies many human disorders and aging. It is therefore surprising that so little is known about how mitochondrial protein synthesis and how the proteins are assembled into complexes. In the frame of a five-year project funded by the Knut and Alice Wallenberg Foundation, we aim to unravel the fundamental molecular mechanisms of mitochondrial protein synthesis, its regulation and connection to respiratory chain assembly. We will employ a wide array of methodology including yeast genetics, human cell culture, biochemistry, and structural biology.
Successful applicants would have a PhD degree in biochemistry, molecular biology or a related field, with preferentially no more than three years of postdoctoral research experience. It is possible that a highly qualified candidate can be employed for 2+2 years. Please submit no later than December 06 a cover letter stating your research interests, curriculum vitae, experience and contact details of three references merged into a single pdf file to email@example.com
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Tagged as: Life Sciences
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