In higher eukaryotes, proteins that lack apparent folded structure are enriched in many vital processes. The laboratory of Edward Lemke studies interactions between intrinsically disordered proteins and structured proteins in vital cellular processes, such as gene regulation, nuclear transport, host pathogen interactions and healthy aging. Since such highly dynamic systems are inaccessible by most conventional approaches, the group applies a multidisciplinary approach combining single molecule, microfluidics, super-resolution techniques and chemical/synthetic biology tools.
As part of an ERC Advanced Grant funded project on “Multiple synthetic organelle design” we are now looking for a Postdoc with past experience in organic chemistry and a strong interest in further expanding chemical/ chemical biology/ synthetic biology tools to develop next generation quantitative single molecule and super resolution based technologies. While the project is particularly well suited for candidates with a strong background in chemistry, the project will be highly interdisciplinary (synthetic organic chemistry, chemical biology, synthetic biology, protein engineering, protein evolution, molecular biology and/or cell biology, biophysics and imaging) and there are multiple aspects to it, that can be filled by one or two different persons with different interests/backgrounds. In all cases, extensive project training will be provided that candidates with little or even prior no-hands on experience in the experimental biosciences but the strong wish to engage into those are particularly encouraged to apply. High interest and motivation are the main selection criteria and candidates from other disciplines that want to venture into these areas are explicitly welcome to apply.
Tagged as: Chemistry, Life Sciences
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