Thinking of doing your PhD in Molecular Biology? The International PhD Programme (IPP) on Gene Regulation, Epigenetics & Genome Stability is offering talented, young scientists the chance to work at the cutting edge of research. The IPP is a community of exceptional scientists working on diverse topics ranging from how organisms age or how our DNA is repaired, to how epigenetics regulates cellular identity or neural memory.
The programme is coordinated by the Institute of Molecular Biology (IMB) — a modern research centre located on the bustling campus of Mainz University in Germany. With a population of 200,000, of which about 40,000 are students, the city of Mainz is charming and open-minded and is within easy reach of cosmopolitan Frankfurt, the Rhine valley region with its castles, vineyards, and nature reserves, and the equally picturesque cities of Wiesbaden and Heidelberg. With Frankfurt airport – the largest airport in mainland Europe – only 20 minutes away, countless European and overseas destinations are within easy reach.
Activities and responsibilities:
In the field of “Epigenetics & Nuclear Dynamics”, “Gene Regulation & Evolution” and “RNA Biology”, the IPP research group of Prof Dr Edward Lemke offers the following PhD project:
Multiple synthetic organelle design
In higher eukaryotes, proteins that lack apparent folded structure are enriched in many vital processes. The Lemke group studies interactions between intrinsically disordered proteins and structured proteins in vital cellular processes, such as gene regulation, nuclear transport, and host pathogen interactions. Since such highly dynamic systems are inaccessible by most conventional approaches, the group applies a multidisciplinary approach combining single molecule, microfluidics, super-resolution techniques and chemical/synthetic biology tools.
As part of an ERC funded project on “Multiple synthetic organelle design” we are now looking for PhD students with a strong interest in further expanding chemical/ chemical biology/ synthetic biology tools to develop next generation quantitative single molecule and super resolution based technologies.
The project is particularly well suited for candidates with a strong background in synthetic organic chemistry, chemical biology, synthetic biology, protein engineering, protein evolution, molecular biology and/or cell biology. However, the project will be highly interdisciplinary, and there are multiple aspects to it, that can be filled by one or two different persons with different interests/backgrounds.
In all cases, extensive project training will be provided that candidates with little or even prior no-hands on experience in the experimental biosciences but the strong wish to engage into those are particularly encouraged to apply. High interest and motivation are the main selection criteria and candidates from other disciplines that want to venture into these areas are explicitly welcome to apply.
What we offer:
· Exciting, interdisciplinary projects in a fully international environment, with English as our working language
· Advanced training in scientific techniques and professional skills
· Access to our state-of-the-art Core Facilities and their technical expertise
· Fully funded positions with financing until the completion of your thesis.
· A lively community of more than 140 PhD students from 40 different countries
Are you an ambitious, young scientist looking to push the boundaries of science while interacting with colleagues from multiple disciplines and cultures? Then the IPP is your opportunity to give your scientific career a flying start!
We seek enthusiastic candidates with a special interest in the following topics:
· Ageing & Disease
· Bioinformatics & Computational Biology
· DNA Repair & Genome Stability
· Epigenetics & Nuclear Dynamics
· Gene Regulation & Evolution
· RNA Biology
Master or equivalent
Interactive personality & good command of English
2 letters of reference
For more details on the projects offered and how to apply via our online form, please visit
The deadline for applications is 27 November 2020. Interviews will take place in Mainz on 25-27 January 2021 if the pandemic situation allows. Otherwise we will inform selected candidates in due time about an alternative online programme.
Starting date: 1 March 2021 – 1 September 2021
Tagged as: Life Sciences
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