Come join us to study the role of ion transporters, including calcium pumps (SPCA2) and sodium-proton exchangers (NHE6, NHE9, NHA2), in human health and disease. Our recent publications focus on the role of these transporters in brain and breast cancer, polycystic kidney disease, autism and Alzheimer disease. You will deploy novel ion sensors to endosomes and lysosomes, and use an innovative PheWAS approach that combines structure-driven analysis and functional screening of human variants to identify, evaluate and predict disease causality. Our experimental reach is broad and multidisciplinary, harnessing the range of available models: (i) bacterial orthologs for structural insights, (ii) yeast for data mining and functional screening of human variants, (iii) 3D organoids and epithelial cultures for cell biological and transport studies and (iv) mouse models and patient databases for pathophysiological insight.
The position is immediately available and requires a recent PhD in the biomedical sciences and general expertise in molecular biology and physiology.
Apply by email with your CV and names of three references.
Tagged as: Life Sciences
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