The Sen laboratory investigates the regulation of T cell dysfunction in cancer and chronic infection and explores epigenetic approaches for T cell engineering. We are interested in recruiting postdoctoral/clinical fellows from a wide variety of backgrounds, including: immunology, cancer biology, single-cell genomics, epigenetics, and bioinformatics. Opportunities are available for wet-lab projects, computational research, or a combination of the two. Individuals will have the opportunity to tackle ongoing questions in the field while growing the research in their own direction.
Our work lies at the interface of human immunology, systems biology, and functional epigenomics – merging clinical observations with mechanistic mouse studies to develop novel therapeutic strategies. Some of our ongoing projects include (i) understanding early fate commitment in dysfunctional T cells, (ii) elucidating tumor context-specific epigenetic changes to guide patient therapies, and (iii) develop new epigenome-targeting strategies to reprogram dysfunctional T cell responses. Fellow will have the necessary resources to carry out an independent research project, including access to technicians, and will hold academic appointments at Massachusetts General Hospital and Harvard Medical School. Fellows will also work closely with senior investigators on high-impact research projects, and have opportunities to present their work at major conferences.
Candidates should be highly motivated and capable of independent work, with an M.D. or Ph.D. in cancer biology, immunology, or bioinformatics/computational biology. Preferred qualifications include in-depth training in next-generation sequencing technologies and bioinformatic analyses, previous immunological/epigenomics research, strong history of publication, and track record for independent funding.
This is a unique opportunity for scientific growth and interaction in a highly collaborative and dynamic environment. This position will provide an outstanding experience for an independent career in science, medicine or biotechnology.
Interested candidates should also send a cover letter with a brief statement of research interests, CV, and the contact details of at least three references directly to Debattama Sen, Ph.D. at firstname.lastname@example.org. Multiple positions are currently available, and this posting will remain open until positions are filled. Applicants are encouraged to apply early. Further information is available at https://senlab.mgh.harvard.edu/.
We welcome and encourage our lab members’ diversity in age, ethnicity, race, gender identity or expression, ability, sexual orientation, socioeconomic status, familial or marital status, mother language, national origin, political affiliation, religious beliefs, veteran status, and other characteristics that enrich our science and perspectives.
Tagged as: Engineering, Life Sciences
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