Position Summary: The Aguirre Lab at Michigan State University focuses on investigating heart development, congenital heart defects, and cardiovascular disease using pluripotent stem cell organoid-based models and state-of-the-art bioengineering approaches. We have made significant contributions to this field recently by reporting the first highly sophisticated human heart organoid model capable of recapitulating aspects of embryonic diabetic cardiomyopathies (Lewis-Israeli et al., 2021, Nature Comms). We have an open position for a motivated postdoc whose primary project will be to develop methods to engineer human heart valves in vitro using hiPSCs and organoid technologies to model aspects of cardiac valve disease. This work will involve work with human iPSCs, scRNA-seq, heart organoids and CRISPR engineering in collaboration with clinicians. The environment in the Aguirre Lab is highly multidisciplinary and collaborative. The successful candidate will also be expected to participate in related secondary projects and collaborations with other IQ labs. The Aguirre Lab is highly committed to the academic and professional development of our trainees.
The Aguirre lab is located in the Institute for Quantitative Health Science and Engineering (IQ) at MSU. IQ has a strong core of leading scientists working collaboratively across broad disciplines including: neuroengineering, motion analytics, developmental and stem cell biology, systems biology, synthetic biology, regenerative medicine, chemical biology and biomedical devices. MSU provides competitive salary and excellent benefits for the position.
Key publications for this position: Lewis-Israeli et al, 2021, Nature Communications; Lewis-Israeli et al., 2021, Biomolecules; Sapp et al., 2021, Scientific Reports; Zhao et al., 2018, Stem Cell Reports; Kurian et al., Circulation, 2015; Aguirre et al., Cell Stem Cell, 2014.
For more information on our lab and on this opportunity contact Dr. Aitor Aguirre (firstname.lastname@example.org).
Tagged as: Engineering, Life Sciences
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