A postdoctoral position is available in the laboratory of Dr. Laufey Amundadottir, at the National Cancer Institute, NIH. The major goal of the lab is to map and understand the biological underpinnings of inherited susceptibility for pancreatic cancer. Our work is focused on gene mapping, genomic and epigenomic characterization of risk loci, and identification of functional risk variants and target genes at risk loci identified by genome-wide association studies (GWAS) and other gene mapping approaches.
This opening is for a highly motivated individual interested in using genetic and genomic approaches to understand the functional consequences of carrying inherited pancreatic cancer risk variants. The lab is highly interdisciplinary and uses state-of-the-art omics technologies such as high throughput sequence-based approaches to assess gene expression, splicing, chromatin interactions and gene regulatory effects. In parallel, a wide variety of molecular and cell biology methods are applied to evaluate the phenotypic consequences of altered regulation or function of susceptibility genes on phenotypes associated with cancer predisposition. The successful candidate will investigate cell type specific effects of inherited risk alleles using sorted populations of pancreatic acinar, ductal and islet cells, as well as the effects of inflammation on molecular phenotypes related to pancreatic cancer risk.
Candidates must have a Ph.D. in molecular biology, genetics, cell biology or biochemistry, and no more than five years of postdoctoral experience. We seek curious and self-motivated individuals with a strong background in genomic and molecular biology methods and an interest in using cutting edge omics approaches. Experience with computational analysis of large scale genetic and genomic datasets is a plus, as well as a strong publication record and effective written and verbal communication skills.
Researchers from traditionally underrepresented groups are encouraged to apply. We highly value diversity and inclusivity.
Tagged as: Life Sciences
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