Humoral responses are a core aspect of the immune response to infections and vaccines, yet we lack robust strategies to predict and precisely manipulate the antibody response. A postdoctoral fellow position is open in the Herati lab, part of the NYU Langone School of Medicine Vaccine Center. We study human immune responses to immunological stimuli by focusing on the interactions of T follicular helper (Tfh) CD4 cells and B cells and the effects on the antibody response. Tfh direct the B cell response in germinal centers, thus we hypothesize that better understanding of the interaction between these cells will create opportunities to shape and manipulate humoral responses.
Our long-term goal is to understand humoral responses in different immunological contexts, including in the settings of infection, vaccines, cancer immunotherapy, and autoimmunity. The more that we understand about the interaction of Tfh and B cells, the better equipped we will be to gain insight and identify opportunities. We use a combination of approaches to study these interactions the cellular and molecular levels. The eventual goal is to devise strategies that allow fine-grained control over antibody responses.
The planned studies will be data-intensive and focused on human immune responses. Competitive candidates will have a doctoral degree and a background in immunology, including substantial experience with flow cytometry, RNAseq, and data science. Passion, enthusiasm, and great communication skills are essential.
To apply, please send your CV, research experience, and contact information for your references to Dr. Ramin Herati at firstname.lastname@example.org.
Tagged as: Life Sciences
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