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Postdoctoral Fellow
Postdoctoral Fellow to study how shear stress activates inflammation Full-time
The Nigam lab at the Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute and the Department of immunology, University of Washington invites applications for a postdoctoral position. Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. The primary focus of the lab seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries. This project, which has been recently awarded a R01, examines how biomechanical stimuli activate inflammatory responses. As a result, successful candidate will be co-mentored by Dr. Ram Savan in the University of Washington Department of Immunology[https://www.immunology.washington.edu/faculty/primary-joint-faculty/ram/].
The successful candidate will perform both exacting bench work and analyses on the resulting RNA-Seq/CHiP-Seq/single cell-Seq/CyTOF datasets. The candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants.
The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses. Prior experience with human iPS cell culture and R programming would be beneficial. Creative, big-picture thinking and dedication to cardiovascular research and immune responses are essential.
The selected candidate will join the vibrant research community at CDBRM and Department of immunology, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment.
The University of Washington and Seattle Children’s Research Institute have strong scientific interactions with Fred Hutchinson Cancer Research Center, Benaroya Research Institute, Institute for Systems Biology, and Brain Research Institute.
Interested applicants should email their CV, brief description of research interests and three references in single PDF file to Vishal.Nigam@seattlechildrens.org and savanram@uw.edu