Senior Bioinformatics Research Scientist/Bioinformatic Research Scientist Full-time

The Epigenetics Group from the Center for Applied Bioinformatics at St. Jude Children’s Research Hospital is looking for a highly motivated and creative Senior Bioinformatics Research Scientist or Bioinformatic Research Scientist to develop and apply innovative analytical approaches to understand the underlying mechanisms that drive pediatric cancers and other human diseases. Working for all different projects together with different PIs, employee could make a valuable difference not only to science but also to pediatric cancer patient curation and survival. Besides the various analysis tasks, we also encourage exploring newly available methods, pipeline development could result in first author, high profile publications, as long as it aligns with our ultimate goal: “Finding cures. Saving children”.

The Center provides a highly interactive environment with collaborative opportunities within the centers including transcriptomics group, genomics group, and genetics group, and across basic and clinical departments, access to high-performance computing clusters, cloud computing environment, novel sequencing platforms such as long reads sequencing technologies, single-cell sequencing at both DNA and RNA level and spatial transcriptomics, innovative visualization tools, highly automated analytical pipelines powered by GPU technology and mentorship from scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The members of this Center could work on broad areas of bioinformatics and gain valuable experiences. The members of this Center also have the opportunity to publish high-profile papers with prominent authorship and file patents for novel biomarker discoveries or novel methods for clinical diagnosis or disease treatment.

Good candidates will have experience building, and optimizing analysis pipelines using available software or installing pipelines for high-throughput next-generation sequence data analysis (such as ChIP-Seq, CutRun, ATAC-Seq, RNA-Seq, scRNA, scATAC, Hi-C/HI-CHIP/CaptureC) under Linux/Unix environment. The successful candidate is expected to have good programming skills in Bash, Python, and R. Also understand basic Epigenetics gene regulation mechanisms (e.g. Histone Modification, Chromatin Accessibility, DNA Methylation, 3D Genome). Experience with deep learning or next flow is a plus.

St. Jude has been frequently made up to Great Place to Work list such as in Fortune magazine’s “Best Workplaces in Health Care & Biopharma™ 2020” list and GlassDoor’s “BEST PLACES TO WORK 2023” list. Salary is highly competitive (comparable to industry) and employee benefits are outstanding. This position is located at Memphis, TN, and relocation assistance is available.

Responsibilities

• Specific responsibilities may involve NGS data quality control, integrative analyses, data visualization, developing and evaluating analytic tools
• Excellent communication skills are essential
• You will work closely with St. Jude PIs to provide standardized/customized analysis, using St. Jude high-performance computing clusters or a cloud computing environment

Minimum Requirments

• Bachelor’s degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master’s degree or PhD preferred.

Senior Bioinformatics Research Scientist

• Minimum Requirement: Bachelor’s degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master’s degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
• Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred

Bioinformatics Research Scientist

• Minimum Requirement: Bachelor’s degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master’s degree with 4+ years of relevant post-degree experience (OR) PhD with no experience.
• Significant experience in at least one programming or scripting language and at least one statistical package, with Python preferred

St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment .

Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.

Other Information

St. Jude is an Equal Opportunity Employer

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St. Jude Children’s Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Tagged as: Computer Science