Senior Scientist l, QTAS & ADME Sciences Full-time NEW

Sr. Scientist I

The Quantitative, Translational & ADME Sciences (QTAS) Department at AbbVie, Inc. in North Chicago, IL is seeking a Sr. Scientist I to join the Non-Regulated Bioanalysis group. This role supports high-throughput processing of samples from biological matrices and LC-MS/MS-based bioanalysis. The ideal candidate will have experience in bioanalytical sample preparation using a range of extraction techniques, operational workflows, data analysis, review, and reporting.

This position is well suited for a detail-oriented, motivated scientist who thrives in a fast-paced, collaborative environment and is committed to delivering high-quality results across multiple projects under tight deadlines. The role also involves partnering with cross-functional teams to align bioanalytical processes with scientific and business needs.

Key Responsibilities

• Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies
• Conduct and optimize sample extraction using protein precipitation, liquid/liquid extraction, or solid-phase extraction methods
• Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs, Sciex 5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst, Sciex OS, and MassHunter
• Troubleshoot pre-analytical and bioanalytical issues
• Maintain accurate documentation of work, including LIMS records, electronic notebooks, test methods, and protocols
• Collaborate with teams across Discovery and QTAS to support bioanalysis
• Train and mentor junior scientists as needed

Qualifications

• Bachelor's Degree or equivalent education and typically 10 years of experience, Master's Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Hands-on experience in bioanalysis of small molecules, peptides, and large molecules in the pharmaceutical industry, including sample preparation and method development
• Strong interpersonal skills with the ability to work independently and collaboratively in a high-throughput setting
• Experience operating automated liquid handling robotic platforms such as Hamilton or equivalent systems
• Experience operating CTC-PAL and Agilent liquid chromatography instruments, as well as LC-MS/MS platforms such as AB Sciex triple quadrupole mass spectrometers or equivalent systems
• Experience with electronic laboratory notebook software and Laboratory Information Management Systems (LIMS)
• Strong instrument and assay troubleshooting skills
• Experience with process development or optimization preferred
• Builds strong relationships with peers and cross-functional partners to enable higher performance
• Learns quickly, grasps the essence, and adapts course when needed
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment that is open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation, and drives innovation to reality

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.