Sr Scientist, Vaccine Technology Full-time

We are seeking a Senior Scientist who is an experienced immuno-oncology researcher to join our dynamic, multidisciplinary Vaccine Immune Cell team in Vaccine Technology. The successful candidate will join a team that develops functional assays on primary immune cells and tumor cells to assess combinatory therapeutics of vaccine and Regeneron’s oncology assets (includes checkpoint inhibitors, bispecific antibodies, and costimulatory bispecific antibodies). Key responsibilities include evaluating the immunogenicity of targets to support cancer vaccine development and assessing antigen-specific T cells to support combination IO therapy development.

As a Senior Scientist in Vaccine Immune Cell team, a typical day might include the following responsibilities:

• Develop strategies to screen and triage novel vaccine candidates
• Independently develop and execute primary human and murine immune cell functional assays, including co-culture assays of immune cells and tumor cells
• Independently design multicolor flow cytometry panels to characterize human PBMCs and other human samples; operate high-parameter flow cytometers and perform analysis
• Perform high-throughput T cell screening to determine antigen-TCR pairing
• In vitro cell engineering, characterization and functional assays, such as TCR engineering
• Lead sample requisition from commercial sources and manage inventory of critical reagents
• Perform data analysis, troubleshoot experiments, and record results in electronic notebook
• Collaborate with multiple teams to achieve shared project goals

This role might be a good fit for you if:

• You are excited to develop novel primary cell assay technologies and learn new techniques to evaluate vaccines
• You have strong communication and presentation skills
• You like to participate in exciting cross-functional projects that involve multiple teams.

To be considered for this role, you may have a PhD with 2+ years postdoctoral or industrial experience, an MS with 5+ years, or a BS with 8+ years of experience in immunology, vaccine research, cancer biology, or related field. We are seeking an individual highly skilled in flow cytometry. The successful applicant should also have >5 years experience in developing primary human and murine cell-based in vitro/ ex vivo functional assays. This position will require the individual to pass a physical before beginning employment.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company’s business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$108,300.00 – $176,700.00

Tagged as: Life Sciences