We are looking for a motivated and talented postdoctoral fellow to join our group. We investigate inherited biochemical disorders of the brain both to answer fundamental biologic questions and to develop new therapies for these devastating diseases.
While individually rare, inherited biochemical disorders (i.e. inborn errors of metabolism, IEMs) occur in approximately 1/1,500 births. The vast majority of patients have neurologic symptoms that do not respond to therapy, even if a treatment can improve biochemical markers of disease in blood. Using genetic, biochemical, and electrophysiologic techniques in cells, model organisms, and human subjects, we investigate the mechanisms that drive neurologic dysfunction in patients with IEMs.
We also are developing novel treatments for IEMs including small-molecule, network-directed, and gene therapies.
Currently available projects include:
We are especially interested in applicants with experience in electrophysiology OR iPSC models. However, these skills are not required.
Tagged as: Life Sciences
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