Neuroscience laboratory at the University of California, San Francisco (UCSF) seeks a qualified, experienced and dynamic Postdoctoral Fellow. The successful candidate will advance our program to use zebrafish in epilepsy research. Our laboratory developed and characterized the first acute and genetic models of epilepsy in zebrafish. Using CRISPR/Cas9 gene editing, we recently generated 40 new zebrafish lines representing rare human epilepsy disorders. We are currently using these unique models in a wide variety of projects, including high-throughput drug screening, neurodevelopmental, and calcium imaging studies, metabolomic studies, and analysis of Variants of Unknown Significance. All of these zebrafish-based projects are supported by grants from the National Institutes of Health.
Using larval zebrafish, we plan to establish new pipelines for the analysis and monitoring of epilepsy and it comorbidities, as well as discover and develop new therapies for these genetic forms of epilepsy. Studies using larval zebrafish incorporate a variety of cutting-edge approaches already established in the lab: electrophysiology, automated behavioral analysis, pharmacology, CRISPR/Cas9 editing, qPCR, microfluidics, computational (MATLAB) analysis, light sheet microscopy, and fast confocal imaging of brain networks in fluorescent reporter fish. We are currently seeking a highly motivated individual to participate in these exciting projects.
If you are interested in a postdoc position in our lab, send an email that includes your CV and contact information for at least two references. Please also send a brief 1-page description of your research interests describing your past research experience, future goals, and how you envision your contribution to the overall research direction of the Baraban Lab. Competitive applicants will have:
· at least one first-author publication in a high-quality journal
· a sincere interest in epilepsy research
· zebrafish experience
UCSF offers an outstanding neuroscience community and desirable San Francisco location. The Baraban Lab particularly acknowledges the acute need to remove barriers to recruitment, retention, and advancement of talented students and postdoctoral fellows from historically excluded populations who are currently underrepresented. Applications from URMs, POC, and women are strongly encouraged.
Tagged as: Life Sciences
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