The lab of Dr. Clément Cochain at the Institute for Experimental Biomedicine and the Comprehensive Heart Failure Center, University Hospital Würzburg, Germany, is offering a postdoctoral researcher position on the topic:
Macrophages in cardiac repair after myocardial infarction
Our research group is interested in understanding immune cell heterogeneity and the mechanisms regulating immune cell function in cardiac repair after myocardial infarction. The applicant will join an international team of researchers and interdisciplinary collaborators to investigate new determinants of macrophage function in ischemic heart repair. The project involves use of a mouse model of myocardial infarction, characterization of cardiac function and repair in mice, immune cell profiling by flow cytometry, and single-cell transcriptomics. The Institute for Experimental Biomedicine and the Comprehensive Heart Failure Center offer access to state-of-the-art facilities and technical support for the methods employed in the project. The applicant will work closely with the PI and other members of the team, perform experiments, participate in institutional seminars, write manuscripts and present results at international conferences.
The position is initially for 2 years, salary according to TV-L. We give priority to applicants with a disability in case of otherwise equal qualifications.
Please send your application including a cover letter, CV and publication list, and contact information of two academic references as a single PDF-file to email@example.com
Recent lab publications related to the project:
Vafadarnejad E, Rizzo G, Krampert L, Arampatzi P, Arias-Loza PA, Nazzal Y, Rizakou A, Knochenhauer T, Reddy Bandi S, Nugroho VA, Schulz DJ, Roesch M, Alayrac P, Vilar J, Silvestre JS, Zernecke A, Saliba AE, Cochain C. Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction. Circulation Research 2020 Oct 9;127(9):e232-e249.
Rizzo, G., Vafadarnejad, E., Arampatzi, P., Silvestre, J.-S., Zernecke, A., Saliba, A.-E., and Cochain, C. (2020). Single-cell transcriptomic profiling maps monocyte/macrophage transitions after myocardial infarction in mice. bioRxiv, 2020.2004.2014.040451.
Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba A-E, Cochain C. 2020. Integrated scRNA-seq analysis identifies conserved transcriptomic features of mononuclear phagocytes in mouse and human atherosclerosis. bioRxiv: 2020.12.09.417535
Cochain C*, Vafadarnejad E*, Arampatzi P, Pelisek J, Winkels H, Ley K, Wolf D, Saliba AE and Zernecke A. Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Circulation Research. 2018 Jun 8;122(12): 1661-1674.
Tagged as: Life Sciences
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