The Stachler Laboratory studies what factors influence preneoplastic progression to invasive cancer. We are especially focused on upper gastrointestinal cancers such as Barrett’s esophagus and esophageal adenocarcinoma. Several projects and opportunities are available including the general themes of: understanding how the inflammatory microenvironment and other external factors influences progression, determining the how the microenvironment drives genomic evolution, further understanding the ‘omic’ makeup of Barrett’s esophagus and gastric metaplasia, using this genomic knowledge to understand how these alterations cause progression into invasive cancer, and using the above information to build biomarker assays for better risk stratification and treatment algorithms. In addition, the person who fills this position will be highly encouraged to explore their own new ideas.
The postdoctoral researcher will work closely with the laboratory PI, Matthew Stachler, as well as the many collaborators within and external to UCSF and help direct the research specialists and technicians within the lab. They will be encouraged to present at scientific conferences and apply for funding opportunities when appropriate.
Some of the many technologies/techniques we utilize within laboratory include: a wide variety of omic technologies (single cell DNA and RNA seq, methylation, spatially defined transcriptome analysis, and others), highly multiplex imaging, primary human cell culture/models, and a murine model of gastroesophageal metaplasia.
For more information on our laboratory please visit our laboratory website at http://stachlerlab.ucsf.edu/.
A MD or PhD in a relevant field is required. The person who fills this position must be enthusiastic, self-motivated, and independent while still willing to ask for guidance when needed. No specific skills are absolutely required, but depending on the project(s) selected to work on, an established understanding of the techniques used is desired and a willingness to learn is a must. Previous experience in genomics, cancer biology, or pathology/multiplex imaging is desired. Understanding of programing and bioinformatics is also a plus but not required.
How to Apply:
To apply or for more information email Matthew.Stachler@UCSF.edu. To apply please send cover letter, CV, and contact information for at least two references.
Tagged as: Computer Science, Life Sciences
POSITION SUMMARYThe Schilling Laboratory at the Buck Institute for Research on Aging is seeking a Postdoctoral Researcher to participate in innovative research...Apply
Postdoctoral Researcher (Research Position, Requisition ID # 28236) Supported by the American Cancer Society, the Stem Cell & Cancer Research...Apply
We are inviting applications for a postdoctoral associate position in the Walczak research group (walczaklab.org). We are an interdisciplinary and...Apply
Overview Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle....Apply
The Huentelman Lab at TGen is searching for a top-notch, collegial Postdoctoral Fellow who is interested in conducting translational neuroscience...Apply
The Agarwal Lab is Recruiting Motivated Scientists for the Postdoctoral and Staff Scientist Positions The OHSU Knight Cancer Institute, known...Apply