The newly created Nephrogenetics unit headed by Prof. Dr. Matias Simons is looking for an enthusiastic postdoc to join our research group at the Institute of Human Genetics of the University Hospital Heidelberg. The general interest of the lab is in the molecular mechanisms underlying hereditary kidney and metabolic diseases. Most of these diseases are caused by single-gene defects and thereby offer unique opportunities to decipher fundamental regulatory pathways of human development and physiology and to develop targeted diagnostic and therapeutic options. Recent publications include Jouandin, Marelja et al, BioRxiv 2021; Perez Marti et al, BioRxiv 2021; Marchesin et al, Cell Rep 2020; Bedin et al, J Clin Invest 2020; Goncalves et al, PloS Genetics 2018; Rujano et al, J Exp Med 2017; Gleixner et al, Cell Rep 2014. We combine human genetics with several experimental approaches, including fly and mouse genetics, cell culture, microscopy and biochemistry. For more info on the lab see www.simons-lab.de.
Within the framework of an ERC Consolidator Grant, we offer an exciting translational project aimed at exploring mechanisms of lipid uptake and metabolism in the kidney, mainly using Drosophila as a model. For this project, we invite applications from individuals with a solid background in cell and developmental biology. Prior experience with Drosophila, lipid and kidney research is an advantage but not a prerequisite. The projects will be carried out in a stimulating work environment with scientific collaborations within the institute, across the Heidelberg life science community (e.g. EMBL, DKFZ) and worldwide.
The successful applicant will have good communication and organisational skills and a PhD in a relevant area (or be in the final stages of completion). We also invite applications from research-oriented MDs. Candidates are expected to be highly motivated and to work independently with a strong work ethic. As we are an international lab, proficiency in English language is a requirement. Applications including a cover letter, a detailed CV including a publication list and contacts of up to three referees should be sent as soon as possible to email@example.com
Diabetic kidney disease, proximal tubules, lipid metabolism, lipodystrophy, lipotoxicity, endocytosis, lipid droplets
Tagged as: Life Sciences
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