Are you an ambitious researcher looking for your next challenge? Do you have an established background in biological mass-spectrometry? Are you interested in new cross-linking methods for chemical and structural proteomics? Do you want to further your career in one of the UKs leading research intensive Universities?
We are seeking to appoint a postdoctoral research fellow with expertise in biological mass spectrometry to develop new cross-linking mass-spectrometry workflows. With a PhD in a relevant discipline, you will have a strong track record in the development and application of mass spectrometry methods to biology discovery, and enthusiasm for interdisciplinary and collaborative research. You will assist the investigators in delivering this research program by implementing state-of-the art mass spectrometry and chemical proteomics workflows using new innovations in chemical- and photo-crosslinking for modification site mapping, and quantitative proteomics.
The post is associated with a major £1.5 million collaborative research programme, funded by the EPSRC in the first instance for 24-months, “A Platform for Chemical Probe Identification and Optimization Facilitating Interrogation of Biological Mechanisms”. To deliver this programme, we are establishing a state-of-the-art facility that leverages our distinct interdisciplinary strengths in (bio)synthetic protein chemistries, chemical probe development and mass spectrometry (MS). It will focus on development and application of chemistry-driven approaches to understand protein function in complex biological environments. These cutting-edge physical sciences methods will enable studies of molecular mechanisms central to plant and animal health, informing treatment and diagnosis of disease, and improving food security.
You will be part of a team based in the School of Chemistry and the Astbury Centre for Structural Molecular Biology with strong links to the School of Molecular and Cellular Biology. You will have access to a superb infrastructure for research in chemical and structural biology, including brand new high-resolution mass-spectrometry instrumentation.
To explore the post further or for any queries you may have, please contact:
Andrew Wilson, Professor of Organic Chemistry
Tel: +44 (0)113 343 1409
Please note: If you are not a British or Irish citizen, from 1 January 2021 you will require permission to work in the UK. This will normally be in the form of a visa but, if you are an EEA/Swiss citizen and resident in the UK before 31 December 2020, this may be your passport or status under the EU Settlement Scheme.
Tagged as: Chemistry