Postdoctoral researcher and PhD student positions are available. The postdoc positions will be supported by grants from National Cancer Institute, PA state fund as well as non-federal research grants. Translational research projects will be partially supported by industry sponsored research funds from pharmaceutical companies, such as AstraZeneca and Bristol-Myers Squibb. The projects will focus on 1) epigenetic alteration and non-coding RNAs; 2) tumor immunology and adoptive T cell therapy; and 3) targeted and epigenetic therapy. Next generation sequencing, single cell analysis, knockout and transgenic animals and gene editing technologies will be used in these projects. Novel computational biology approaches and resources will be provided from our computational biology team in the lab (http://188.8.131.52/home/). The position requires experience in cellular and molecular biology, such as the experimental technology on molecular mechanisms of anti-cancer drug sensitivity and resistance. Previous experience in tumor immunology, knock-out and transgenic animals, RNA biology, epigenetics, cancer biology and cancer genomics would be helpful. We are also welcome the candidates, who are trained in other fields such as developmental biology, genetics and genomics, to apply these positions.
References for project 1:
Cancer Cell 2014; 26(3):344-57.
Cancer Cell 2015; 28(4):529-40
Nat Struct Mol Biol 2016; 23(6):522-30
Cancer Cell 2018: 34(4):549-560
References for project 2:
New England Journal of Medicine 2003; 348(3): 203-13
Nature 2011; 475(7355): 226-30
Nature Cancer 2021; accepted
References for project 3:
Science Translational Medicine 2017; 9(400)
Nature Communications 2019;10(1):733.
Cell Reports 2020; 32 (2), 107884,
The candidate for postdoc must have a Ph.D. degree and have less than 3 years postdoctoral experience in a related field. Candidates are expected to work independently, be highly creative and self-motivated. Please forward a cover letter, an updated c.v. including a list of your publications and the email addresses of referees to:
Lin Zhang MD, Harry Fields Research Professor
Lab: 1233~1237; Office: 1207
Institute for Translational Medicine and Therapeutics
Center on Research for Reproduction and Women’s Health
Abramson Cancer Center
Department of Obstetrics and Gynecology
University of Pennsylvania School of Medicine
Tel: 215-573-4780 (office); 215-573-7947 (lab); 215-573-4785 (lab)
Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation’s first medical school) and the University of Pennsylvania Health System, which together form a $8.6 billion enterprise.
The Perelman School of Medicine has been ranked among the top medical schools in the United States for more than 20 years, according to U.S. News & World Report’s survey of research-oriented medical schools. The School is consistently among the nation’s top recipients of funding from the National Institutes of Health, with $494 million awarded in the 2019 fiscal year.
The University of Pennsylvania Health System’s patient care facilities include: the Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center—which are recognized as one of the nation’s top “Honor Roll” hospitals by U.S. News & World Report—Chester County Hospital; Lancaster General Health; Penn Medicine Princeton Health; and Pennsylvania Hospital, the nation’s first hospital, founded in 1751. Additional facilities and enterprises include Good Shepherd Penn Partners, Penn Medicine at Home, Lancaster Behavioral Health Hospital, and Princeton House Behavioral Health, among others.
Penn Medicine is powered by a talented and dedicated workforce of more than 43,900 people. The organization also has alliances with top community health systems across both Southeastern Pennsylvania and Southern New Jersey, creating more options for patients no matter where they live.
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Tagged as: Life Sciences
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