The Cluster of Excellence (EXC2180) “Image-Guided and Functionally Instructed Tumor
Therapies (iFIT)” is a multidisciplinary and interdisciplinary research program that focuses on
understanding tumor biology and the development of novel diagnostic and therapeutic
approaches for cancer.
The iFIT research group of Jun. Prof. Dr. Josef Leibold is looking for a
Postdoc (f/m/d) in Functional Immunogenomics.
The Leibold Lab (https://www.feucht-leibold-labs.com), supported by an ERC Starting Grant
and the iFIT Excellence Cluster, develops innovative therapeutic approaches for solid tumors.
These include chimeric antigen receptor (CAR) T and NK cells combined with targeted
therapies and immune-modulatory agents. By leveraging advanced technologies like
CRISPR/Cas9 genome engineering and cutting-edge mouse models, the lab aims to restore
immunosurveillance mechanisms and enhance immunotherapeutic strategies for late-stage
and metastatic cancers.
Key publications:
Leibold J*, Tsanov K*, Amor C* et al. Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature Cancer 2024. Link
Paffenholz et al. Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. PNAS 2022. Link
Amor C*, Feucht J*, Leibold J* et al. Senolytic CAR T cells reverse senescence-associated pathologies. Nature 2020. Link
Leibold J*, Ruscetti M*, Cao Z* et al. Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis. Cancer Discov 2020. Link
Your key responsibilities:
Your profile:
molecular biology methods
Benefits for you:
innovative and impactful research field
About Eberhard Karls Universität Tübingen
The Eberhard Karls Universität Tübingen is an international and interdisciplinary research institution and has been awarded the status of a University of Excellence. Tübingen houses three internationally recognized research clusters in cancer immunology (iFIT), machine learning and AI (ML), and infection medicine (CMFI). The University Hospital has a strong track record in translational research and houses innovative clinical centers (Comprehensive Cancer Center, German Cancer Consortium, National Center for Tumor Diseases).
How to apply:
The earliest possible start date is May 2025 and the position is offered for 2 years with
plans for further extension. Severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen is committed to increase the percentage of female scientists, and therefore encourages women to apply for this position. The Administration of the University Hospital is responsible for all employment matters.
Please send your application forms including a cover letter, your CV as well as contact details for two references via e-mail (single pdf) or in written form to:
Josef Leibold, M.D.
Juniorprofessor for Functional Immunogenomics
Cluster of Excellence iFIT (EXC2180)
Röntgenweg 11
72076 Tübingen, Germany
Email: [Please click the Apply button for the link or address]
Tagged as: Life Sciences
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ApplyPlease send your application to josef.leibold@med.uni-tuebingen.de
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