Several postdoctoral positions are available in the group of Taija Mäkinen at Uppsala University. The lab studies fundamental mechanisms of tissue morphogenesis in the vascular system. The aim is to understand how endothelial cells communicate with the tissue environment to co-ordinate vascular morphogenesis and formation of functionally specialised blood and lymphatic vessel types. To do so, the group utilises advanced mouse genetic tools for cell-type specific targeting and lineage tracing, combined with state-of-the-art cell and molecular biology techniques (including single cell RNA sequencing, flow cytometry, confocal, light-sheet and super-resolution microscopy). For more details about the group’s research please see: http://www.makinenlab.com/
Selected recent publications from the laboratory: Frye et al, eLife 2020; Martinez-Corral et al, Nat Commun 2020; Zhang et al, Nat Commun 2018; Frye et al, Nat Commun 2018; Zhang et al, Development 2018; Wang et al, Development 2017; Martina-Almedina et al, J Clin Invest 2016; Martinez-Corral et al, Circ Res 2015; Stanczuk et al, Cell Rep 2015; Tatin et al, Dev Cell 2013.
Project description. The selected candidate(s) will work on one of the following topics: 1) functional characterisation of organ-specific lymphatic endothelial progenitor cells, 2) novel (organ-specific) functions of lymphatic endothelium in homeostasis and disease, or 3) pathogenic mechanisms of PIK3CA-driven vascular malformations.
Qualifications. We are looking for highly motivated individuals with a PhD and research background in molecular or cell biology, developmental biology or biochemistry, and a proven track record of successful scientific work. Strong background in molecular/cell biology, mouse genetics, flow cytometry and/or imaging is required.
How to apply. To apply, please send your CV together with the names of three references and a short description of yourself and the motivation to join the group to: firstname.lastname@example.org
Tagged as: Life Sciences
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