Senior Research Technician – Neurology Full-time

Position Summary
We are seeking a Senior Research Technician to conduct research projects and assist with research activities in the Weihl Lab at Washington University School of Medicine. The Weihl Lab is focused on understanding the molecular and cellular mechanisms underlying muscular dystrophies to develop targeted gene-based therapies. We employ a wide variety of techniques using mouse models, primary cell culture, and patient derived iPSCs. Treatment modalities involve ASOs, siRNAs, AAVs, CRISPR/Cas9, or PRIME editing.

The position independently performs complex research studies, experiments, and assays. The successful hire will have a skill set to perform animal studies, cell culture, molecular biology, biochemistry, and immunohistochemistry experiments. 

To apply, please use the Application URL given.

Job Description

• Primary Duties and Responsibilities
• Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians.
• Performs biochemical and molecular biological experiments, including but not limited to, immunohistochemistry, immunocytochemistry, fluorescence microscopy, DNA / RNA extraction, sanger sequencing, PCR, RT- quantitative PCR, western blotting, and cloning.
• Assists with experiments and muscle histology.
  Performs tissue culture (primary mouse or human myoblasts, iPSCs) and downstream experiments and screening assays.
• Provides for data entry and current data files on research projects. Monitors data to ensure consistent quality.
• May perform preliminary statistical analysis of data.
• Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
• Assists in the training and development of technicians, acting as a group leader.

Working Conditions

This position works in laboratory environment with potential exposure to biological, chemical and radioactive hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Preferred Qualifications

• Hands-on work experience with mice.
• Ability to assist with a mouse colony, including handling and monitoring mice, and small procedures.
• Experience with molecular cloning, PCR, Western blot, cell culture, transfection, and fluorescence microscopy.
• Working knowledge of computer software and general lab equipment.
• Motivated to manage an independent lab project.
• Reliable, conscientious, and detail-oriented.
• Demonstrated ability to be highly productive in a collaborative work environment.
• Demonstrated ability to work independently and communicate with laboratory staff and investigators.
• Ability to maintain complete and organized records/reports. 

Required Qualifications 

Master’s degree with two years of experience in a laboratory setting or an equivalent combination of education and experience equaling seven years.

Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. 

Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits. 

EEO/AA Statement
Washington University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration without regard to an individual’s sex, race, color, religion, age, disability status, protected veteran status, national or ethnic origin, gender identity or expression, sexual orientation. Women, minorities, protected veterans and the disabled are strongly encouraged to apply. 

Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply. 

Applicant Instructions
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Tagged as: Life Sciences