Associate Scientist Biologics AD Full-time

Associate Scientist, Protein Characterization By Mass Spectrometry In Malvern, PA

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

The Associate Scientist will work in the Characterization group within Analytical Development to develop, design and perform mass spectrometry assays in support of product characterization and process development activities. Duties and responsibilities include but are not limited to:

1. Execute intact/reduced/subunit LC/MS assays for characterizing mAb products
2. Perform metabolite analysis using targeted LC/MS methods
3. Perform method qualifications and write reports to support analytical development and manufacturing process development, process validations, manufacturing investigations, structure/function characterization, and IND/BLA filing.
4. Maintain laboratory notebooks and prepare written protocols and reports in a Good Manufacturing Practice (GMP) compliant manner.

Qualifications:

• B.S./B.A. in Analytical Chemistry, Biochemistry, Biotechnology, Protein Formulations, Chemical Engineering, or a related field with 2+ years of experience, performing progressively advanced duties or the equivalent training/experience

Required:

• Hands-on experience with Mass Spectrometry
• Experience working in a GLP/GMP environment
• Good written and verbal communication skills

Preferred:

• Experience with mass spectrometers and associated software from different vendors (Waters, Thermo, Sciex, Shimudzu)
• Experience with 3rd party MS software (eg., Protein Matrix, Genedata Expressionist, etc.)
• Experience with characterization of antibody drug conjugates (ADCs)
• Experience and understanding of pharmaceutical development chemistry, manufacturing and controls (CMC) processes and regulatory requirements for protein biologics

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.