In Vivo Scientist/ In vivo Technologist – Cancer Immunology Full-time

In Vivo Scientist/In Vivo Technologist – Cancer Immunology

At AstraZeneca, we are driven by a shared purpose to push the boundaries of science and transform the lives of patients living with cancer. We are seeking a highly motivated and independent Scientist with expertise in Immunology, Oncology, and Cancer Immunology to join our Early Discovery Oncology Bioscience team in Gaithersburg, MD. This role offers the opportunity to contribute to groundbreaking Immuno-Oncology research, focusing on identifying new targets for cancer immunotherapy and overcoming resistance to existing treatments. You will design and conduct in vivo experiments, utilizing your skills to assess candidate oncology drugs and explore novel cancer therapeutics. This laboratory-based position involves developing methodologies, generating scientific data, and collaborating within a dynamic team environment. Are you ready to make a difference?

Accountabilities

In this role, you will analyze, represent, interpret, and present experimental results systematically. You will write protocols, reports, and record detailed experimental procedures. Working in a team/matrixed environment, you will achieve goals and contribute to the advancement of innovative research.

Essential Skills/Experience

• BS or MS in biology, biotechnology, immunology or related field with a minimum of 3 years “hands-on” in vivo experience.
• Developing and working with different in vivo mouse models of cancer including subcutaneous, orthotopic and transgenic/inducible models in both immunocompetent and immunodeficient animals.
• Skilled in different routes of drug administrations.
• Conducting in vivo pharmacology studies.
• Sampling, profiling, and processing of tissue samples for downstream applications.
• Maintain records, ordering, and keeping track of studies reagents.
• In vitro cell culture experience.
• In vivo animal modeling (mouse syngeneic, autochthonous and/or xenograft cancer models) to understand the interactions of small molecules, antibodies, and other therapeutic modalities with the immune system.
• Experience using in vitro assays with both primary and immortalized cells, and use of analytical methods such as FACS, ELISA, immuno-fluorescence microscopy, immunoblotting and others as needed.
• Ability to work both independently as well as within project teams.
• Ability to lead from the bench in problem solving and in the development of innovative solutions.
• Excellent communication and organizational skills.
• The ability to independently review, analyze, and interpret experimental results.

Desirable Skills/Experience

• Basic molecular biology techniques.
• Basic immunological techniques.
• Metastatic models/humanized models.

About AstraZeneca in Gaithersburg, MD

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

AstraZeneca is where the brightest minds come together to share knowledge and grow collectively. Our diverse team seamlessly collaborates across disciplines, combining the best of academia and industry to tackle complex challenges. With one of the broadest Oncology pipelines in the industry, we offer unparalleled opportunities to work with novel drugs and make bold moves that transform cancer treatment. Empowered by our supportive network, we embody courage and curiosity, taking smart risks to improve patient outcomes.

Ready to join us on this exciting journey? Apply now to be part of our mission to eliminate cancer as a cause of death!