Manager Scientist Full-time

Manager Scientist

Location: Swiftwater, PA

About the Job

The Upstream Process Development group as a part of Manufacturing Technologies/ Industrial Affairs department supports several projects including:

• Generation of recombinant baculovirus working virus banks (seeds) for manufacturing of seasonal influenza Flublok and COVID vaccines
• Upstream process development at small and mid scales
• Process techtransfer and yield improvement
• Manufacturing support

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

Main Responsibilities

• Responsible for leading and mentoring a team of junior personnel and educating / maintaining technical knowledge in workforce.
• Oversee all aspects of baculovirus plasmid generation.
• Foster a culture of scientific excellence, collaboration, and accountability.
• Perform routine molecular biology tasks such as primer design, DNA construct design, PCR amplification, cloning, plasmid purification, DNA purification, restriction endonuclease digest, DNA sequencing and analysis, bioinformatics analysis of the sequences from different databases
• Design, analyze and document experiments, maintain proper records electronically and in lab notebooks
• Effectively communicate results in group and department meetings
• Contribute to lab organization, reagent tracking and ordering
• Ensure that work performed is conducted in a safe and compliant manner in adherence with SOPs/SWIs and protocols
• Coordinate data capture and tracking information
• Partner with Upstream Process Development, Quality Control, Quality Assurance, and Regulatory Affairs teams.
• Write and review protocols and reports
• Serve as Molecular Biology SME to tech transfer and manufacturing support

About You

Education / Experience

• Bachelors Degree in Molecular Biology, Chemical Engineering, Biochemical Engineering, Biochemistry, Biotechnology, life sciences or other related fields.
• Masters Degree in Molecular Biology, Chemical Engineering, Biochemical Engineering, Biochemistry, Biotechnology, life sciences or other related fields. – preferred.
• 2+ Years Hands on experience in molecular biology with previous experience in Site Directed Mutagenesis, Gibson assembly, seamless cloning procedures
• A combination of education and experience will be considered.
• Experience with purification of DNA from baculoviruses
• Familiarity with Restriction Fragment Length Polymorphism (RFLP) and Femto Pulse experiments is a plus
• Experience in baculovirus protein expression system and insect cell cultures is highly desirable.
• Contribute to lab organization, reagent tracking and ordering
• Hands-on experience in DNA sequence analysis, construct design using SnapGene, or similar software is a plus
• Ability to plan and conduct laboratory experiments, evaluate, and interpret data
• Ability to work within team environment and multitasking is a plus
• Strong written and verbal communication skills
• Detail-oriented and ability to prioritize assignments
• Ability to work with minimum supervision
• Experience in cell culture procedures and associated aseptic techniques is a plus
• Fluent in both written and spoken English
• Strong experience in Microsoft Excel, Word and Power Point is important

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.