PBPK Scientist, PK/PD & Pharmacometrics Full-time

Scientific Director

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Eli Lilly and Company is committed to using its innovation-based strategy to discover, develop and deliver cutting-edge medicines that help improve the lives of people. In support of this goal, the PKPD & Pharmacometrics (PMx) organization provides leadership and technical expertise to support the discovery and development of new medicines from preclinical lead molecule identification to clinical post-drug approval, with the goal of identifying and developing the right drug with the right dose for the right patient using model-informed drug research and development (MIDD) approaches. To further advance the science in this discipline, we are seeking a scientific director who is experienced in PBPK modeling.

We are passionate about making an impact in the lives of our patients, developing people to their full potential, and pushing the boundaries of science. Consider joining Team Lilly to contribute to Lilly's drug discovery and development efforts.

Key Responsibilities

• Provide scientific leadership to project teams to support the selection of the right target, molecule, dose, patient population, and development strategies.
• Develop and execute modeling strategies, contribute to project team discussions, and guide decisions with quantitative approaches in drug discovery and/or development.
• Communicate quantitative data, both internally and in the scientific community.

Basic Qualifications

• PhD in Pharmacokinetics/Pharmacodynamics, Pharmacology or a related discipline and at least 5+ years of relevant work experience with physiologically based pharmacokinetic modeling in the pharmaceutical industry or contract research organization.
• Knowledge and expertise advancing and implementing PBPK model-informed approaches in drug discovery, development, and regulatory submissions.
• Strong interpersonal communication skills, including demonstrated experience working in a team environment.
• Direct experience using relevant software such as Simcyp, PKsim, Gastroplus, etc.

Additional Skills/Preferences

• Adept at working with cross-functional colleagues.
• Excellent self-management and organizational skills.