Postdoc Data Science Oncology Full-time

Postdoctoral Data Science Oncology

Johnson & Johnson Innovative Medicine (JJIM), a Johnson & Johnson company, is recruiting for a Postdoctoral Data Science Oncology to be located at our office in either Spring House, PA; Titusville, NJ; Cambridge, MA.

The successful candidate will work closely with experimental and clinical collaborators, applying cutting-edge statistical and machine-learning approaches to identify immune cell states, biomarkers, and mechanisms underlying response to cancer therapy. This position is ideal for a postdoc eager to translate complex data into biological insight and clinically relevant hypotheses.

Key Responsibilities:

• Perform comprehensive computational analyses of single-cell and spatial transcriptomics datasets to characterize the tumor microenvironment in bladder cancer.
• Apply advanced statistical and machine-learning methods to identify biomarkers, immune cell states, and biological mechanisms associated with BCG immunotherapy response.
• Integrate multi-modal datasets, including scRNA-seq, spatial transcriptomics, bulk RNA-seq, proteomics, and clinical metadata, to achieve a systems-level understanding of tumor–immune interactions.
• Incorporate imaging and pathological covariates alongside molecular data to generate clinically interpretable insights and inform treatment strategies.
• Lead the synthesis of computational findings into clear, compelling scientific narratives and drive manuscript preparation for submission to high-impact journals.
• Collaborate closely with experimental scientists and clinical teams to interpret results, refine hypotheses, and guide translational research directions.
• Present findings internally and externally at scientific meetings and seminars.

Required Qualifications:

• PhD in Computational Biology, Bioinformatics, Data Science, Systems Biology, Biostatistics, or a related quantitative discipline.
• Strong experience analyzing high-dimensional omics data (e.g., single-cell RNA-seq, spatial transcriptomics, bulk RNA-seq).
• Proficiency in computational programming languages such as R and/or Python. Demonstrated ability to work independently on complex data analysis projects and communicate results clearly.
• Strong scientific writing skills and a track record for first-author publications.

Preferred Qualifications:

• Experience with tumor immunology, cancer biology, or immunotherapy datasets.
• Familiarity with spatial transcriptomics platforms and/or imaging-based analyses.
• Experience integrating multi-modal molecular and clinical datasets.
• Prior exposure to translational or clinically oriented research environments.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is: $95,000.

Additional Description for Pay Transparency: Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Employees are eligible for the following time off benefits: – Vacation – up to 120 hours per calendar year – Sick time – up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year – Holiday pay, including Floating Holidays – up to 13 days per calendar year – Work, Personal and Family Time – up to 40 hours per calendar year Additional information can be found through the link below.