Postdoc in DNA/RNA nanotechnology for cell regulation Full-time

Postdoc In DNA/RNA Nanotechnology For Cell Regulation

The interdisciplinary Nanoscience center (iNANO) at Aarhus University invites applications for a 2-year postdoc position. This position offers an exciting opportunity to join an ERC-funded research project (BioRIcON) focused on developing nucleic acid-based artificial motors and devices for precise regulation of key cellular processes.

You are expected to contribute to a project focused on developing a novel class of nucleic-acid based, biohybrid interlocked molecules (BIMs) for precise biomolecular regulation. This research involves a multifaceted approach, including: i) the design and assembly of nucleic acid-based interlocked motors and switches; ii) establishing the principles to operate them in vitro and in cellular settings; iii) study of their properties and functions for enhanced cell regulation; and iv) application of these adaptative systems for reversible control of cell function, exploring their potential biomedical use.

Applicants should hold a PhD in chemistry, molecular biology, biochemistry, nanoscience, nanotechnology, medicinal chemistry or similar, and must have experience with nucleic acid chemistry and/or DNA/RNA nanotechnology. Expertise in cell assays/cell biology and single-molecule microscopy techniques (such as EM, TIRF, AFM microscopy) will be a major advantage. Experience with aptamer development, flow cytometry, binding assays and confocal microscopy will be an advantage. The ideal candidate should be socially oriented, self-driven, and motivated, with strong communication skills and the ability to work as part of an international team. Proficiency in written and spoken English is a requirement for the position.

Further information about the position may be obtained from Assistant Prof. Julián Valero jvalero@inano.au.dk. Interested candidates are encouraged to contact for further details about the position.