Postdoc in Microphysiological Systems for Tumor Biology Full-time NEW

Postdoc in Microphysiological Systems for Tumor Biology

We are looking for a postdoctoral fellow with the task of validating and developing new systems to emulate cancer microenvironments. The fellow will work on multidisciplinary projects collaborating with research groups across KTH, Karolinska Institutet, SciLifeLab, and Karolinska Hospital. The host environment will be the Division of Nanobiotechnology, SciLifeLab, KTH with the group of Professor Anna Herland.

The project aim is to simulate the tumor microenvironment at two levels of complexity:

• Tumor-stroma interactions to uncover self-reinforcing ligand secretion patterns, which could become the target of novel therapies. This approach will be strongly supported by in silico digital-twin-like models of these interactions.
• Vascularization of tumor models to enable improved studies of immunotherapies and combinatorial therapies. This approach will be supported with multimodal in vitro and in vivo modeling as well as clinical material.

The work includes designing and developing new models and validating existing ones.

Your specific duties will include:

• Design of microphysiological systems and organ-on-chips
• Fabrication and validation of microphysiological systems and organ-on-chips
• Collaborations with computational scientists and cancer biologists
• Coordination of activities between project partners
• Supervision of research engineer/master's student in the projects

Requirements

• A doctoral degree or an equivalent foreign degree in bioengineering, biotechnology, microtechnology or other relevant fields.
• Research expertise with at least 2 peer-review articles published or in advanced manuscript for

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
• Experience in microsystem and microfluidic design and fabrication
• Experience in cancer biology projects
• Teaching and supervision experience
• Excellent ability to collaborate and cooperate with researchers and industry from different disciplines
• Excellent ability to work independently
• Awareness of diversity and equal opportunity issues, with a specific focus on gender equality
• Excellent communication skills

Great emphasis will be placed on personal skills.