Postdoctoral Researcher in Molecular Immunology Full-time

Postdoctoral Researcher in Molecular Immunology

Do you want to contribute to top quality medical research?

We are looking for a postdoctoral candidate that will work on advanced reconstitution methods, primary human immune cells and advanced imaging methods to quantitatively investigate immune responses to foreign antigens.

The project will be performed at the Cell Signalling, Immunity and Nanoimaging (CSI:Nano) Lab and Karolinska Institute, led by Assoc. Prof. Erdinc Sezgin.

SciLifeLab and KI are excellent places to carry out basic biomedical research with clinical potential. Our lab is in the intersection of biology, chemistry, physics and engineering, aiming to reveal the molecular codes of cellular physiology and diseases. The candidate will greatly benefit from this interdisciplinary environment and unique infrastructure.

This position is for 2 years full-time employment with potential extension upon mutual agreement.

Application Deadline: 1 May 2026

Start Date: 1 June 2026

Your Mission

The postdoctoral fellow will develop advanced synthetic biology tools to reconstitute immune cell signalling and analyse them quantitatively with advanced imaging.

The project involves:

• applying model membrane biology tools (GUVs, GPMVs, SLBs, BSLBs)
• imaging tools (FLIM, spectral imaging, flow cytometry)
• working with primary human immune cells from healthy donors
• development of software and data analysis tools to characterize multiparametric datasets
• work in close collaboration with the other CSI:Nano lab members as well as other labs at SciLifeLab and KI

Your Profile

To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

• BSc and MSc in life science, natural sciences or engineering
• PhD in areas: cell and molecular biology, biomedicine, biophysics
• Strong interest in molecular immunology
• Strong expertise in model membrane tools and reconstitution of proteins
• Strong expertise in imaging technologies, particularly spectral imaging and FLIM
• Strong expertise in primary immune cell handling
• Strong expertise in chemical biology probes
• Expertise is proximity assays are advantageous.
• Strong expertise in image analysis
• Independent working skills, teamwork spirit and willingness to help PhD/master students

What Do We Offer?

CSI:Nano Lab members come from international and interdisciplinary backgrounds, such as physics, chemistry, biomedicine, molecular biology and engineering. Our working language is English. In the lab, we advocate for diversity, equity and inclusion; promote open science and data sharing; encourage lab members to attend conferences; and foster healthy feedback culture. Moreover, the supervisor has open-door policy for meetings and brainstorming.

CSI:Nano Lab gives the fellows the opportunity to develop and/or apply state-of-the-art imaging methodologies to solve biological mysteries. Necessary training on the advanced bioimaging technologies will be given to the fellows. CSI:Nano Lab gives the candidates opportunity to become fully independent researchers in interdisciplinary science within years.

Karolinska Institute and SciLifeLab offer a creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday, parental leave and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

SciLifeLab is an institution for the advancement of molecular biosciences in Sweden. It leverages the unique strengths of individual researchers across Sweden into a focused resource for the life science community. SciLifeLab provides access for thousands of researchers to the cutting-edge instrumentation and deep scientific expertise necessary to be internationally competitive in bioscience research. The facilities and expertise at SciLifeLab create a unique environment for carrying out health and environmental research at the highest level.

The postdoctoral researcher will be based at SciLifeLab Solna where the working atmosphere is international with English as the working language.

Location: SciLifeLab, KI, Campus Solna

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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