Postdoctoral researcher in Single-molecule biophysics Full-time NEW

Postdoctoral Researcher In Single-molecule Biophysics

Are you interested in exploring fundamental mechanisms in genome biology, with the support of skilled and supportive colleagues in an international environment? Are you looking for an employer that invests in a sustainable workforce and offers safe, favorable working conditions? We welcome you to apply for a postdoctoral position at Uppsala University. The Department of Cell and Molecular Biology is organized into seven research programmes which all focus on different areas of cell and molecular biology: Computational Biology and Bioinformatics, Microbiology and Immunology, Molecular Biology, Molecular Biophysics, Molecular Evolution, Molecular Systems Biology and Structural Biology. The scientific basis of what we do lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering sciences and physics. In total, we are over 200 staff and ~60 PhD students. The Deindl lab offers a stimulating multidisciplinary environment where you will work closely with experts in biophysics, biochemistry, structural and molecular biology. Our overall mission is to investigate the molecular mechanisms underlying genome-interacting processes using a highly multidisciplinary approach that combines advanced single-molecule fluorescence imaging with a range of structural, biophysical, and biochemical techniques.

Duties: The postdoctoral researcher will investigate fundamental mechanisms underlying programmable DNA recognition and genome reorganization. This project offers a unique opportunity to develop innovative experimental approaches aimed at resolving key questions in molecular specificity, DNA remodeling, and cellular genome dynamics. The successful candidate will combine advanced single-molecule fluorescence microscopy with a diverse toolkit of molecular biology and in vitro biochemical approaches to advance our understanding of this emerging area.

Requirements: We are seeking a highly motivated candidate with a PhD in biophysics, biochemistry, physics, molecular biology, cell biology, or a related field. The degree must be obtained by the time the employment decision is made. In accordance with eligibility requirements, priority will be given to candidates who obtained their PhD no more than three years before the application deadline. The three-year period is calculated from the application deadline and may be extended in cases of documented special circumstances, including sick leave, parental leave, or duties in labour unions. The candidate should be able to work independently and must have excellent proficiency in English, as the position is based in an international research environment. We value strong collaborative skills, self-motivation, and a genuine interest in basic research, particularly in addressing fundamental biological questions through quantitative approaches. Prior experience and a strong interest in fluorescence microscopy, single-molecule microscopy, and related quantitative approaches are highly valued. Experience with protein-DNA or nucleic acid-protein complexes, DNA recognition systems, genome engineering approaches, or in vitro biochemical reconstitution will be considered an advantage.

About the employment: The employment is a temporary position of two years with the possibility to extend to three years according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100%. Starting date as soon as possible or as agreed. Placement: Uppsala.

For further information about the position, please contact: Sebastian Deindl, sebastian.deindl@icm.uu.se. Please submit your application by June 15, 2026, UFV-PA 2026/1516.

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden's most exciting workplaces.

Read more about our benefits and what it is like to work at Uppsala University https://uu.se/om-uu/jobba-hos-oss/.

The position may be subject to security vetting. If security vetting is conducted, the applicant must pass the vetting process to be eligible for employment.

Submit your application through Uppsala University's recruitment system.

Type of employment – Temporary position.

Employment expires – 2028-06-30.

Contract type – Full time.

First day of employment – 2026-07-01.

Salary – Individuell lönesättning.

Number of positions – 1.

Full-time equivalent – 100.

City – Uppsala.

County – Uppsala län.

Country – Sweden.

Reference number – UFV-PA 2026/1516.

Published – 06.May.2026.

Last application date – 15.Jun.2026.