We are currently seeking a Postdoctoral Scientist to work within the lab of Dr. Michelle Wang, Professor of Physics, J.G. White Distinguished Professor in the Physical Sciences, and Howard Hughes Medical Institute (HHMI) Investigator at Cornell University in Ithaca, NY. We aim to understand how fundamental processes, such as transcription and replication, can alter DNA topology and how these topological changes impact these processes. We operate at the intersection of physics and biology – pioneering single-molecule techniques to investigate the mechanics and topology of fundamental DNA processes and theoretically modeling these processes using statistical mechanics and thermodynamics. Our studies have revealed the essential roles of mechanics, topology, and biomolecular condensation in fundamental DNA processes. These studies demonstrate how complex biological phenomena can arise from simple physical properties inherent to biomolecules.
More information about the lab and links to publications can be found on our website: .
About the position:
The successful candidate will carry out projects to investigate the mechanics and topology of fundamental DNA processes using state-of-the-art single-molecule methods pioneered in the lab. The Wang lab has invented several single-molecule manipulation techniques, including the angular optical trap (AOT), the DNA unzipping mapper, tracker, and staller, and the nanophotonic standing-wave array trap (nSWAT). The candidate will also have the opportunity to develop novel instruments for enabling new topology studies, gain an in-depth understanding of data via theoretical and computational modeling, and investigate the in vivo significance through cellular and genomic studies. They will be part of a dynamic, collaborative team and have the opportunity to contribute to unique and exciting science.
Application Instructions:
Candidate requirements:
Physical Requirements
Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).
Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.
Please Note:
This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.
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Compensation and Benefits
Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our site to learn more.
Compensation Range
$70,000.00 (minimum) – $80,500.00 (midpoint) – $91,000.00 (maximum)
Pay Type:
Annual
HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate’s education, previous experiences, knowledge, skills and abilities, as well as internal consistency when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.
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