Principal Investigator, SIgN Full-time

Principal Investigator, SIgN

We are looking for an independent scientist capable of leading a research program in Immunology & Inflammation research, fostering collaborations, securing competitive grants, and contributing to translational outcomes.

Core Competencies (Broad & Non-Restrictive)

• Strong expertise in molecular and cellular biology, with experience in genomics or epigenomics-related approaches.
• Ability to interpret and integrate NGS datasets (e.g., transcriptional or chromatin profiling such as ChIP-seq) as part of their research program.
• Demonstrated track record in securing peer-reviewed national grants.
• Experience working within Singapore’s research ecosystem and building multi-institutional partnerships including with clinical partners.
• Interest and experience in translating scientific discoveries toward clinical or industry impact (e.g., IP, collaborations, translational grants).

Key Responsibilities

• Lead an independent research program aligned to the lab’s and institute’s strategic priorities, with flexibility in disease area or biological focus.
• Develop a sustainable funding pipeline as PI/Co-PI across basic, clinical, and translational research schemes.
• Guide research direction and technical strategy, including experimental and/or computational aspects of high-throughput sequencing workflows.
• Mentor junior researchers (students, fellows, and research staff) and foster scientific development within the team.
• Strengthen translational pathways, including IP generation, collaboration with tech-transfer offices, and engagement with relevant industry or clinical stakeholders.

Requirements

Education & Experience

• PhD in a relevant Life Science field.
• Approximately 5-10 years post-PhD research experience with evidence of independence and leadership.

Technical Strengths

• Proficiency in molecular biology and functional assays.
• Experience with genomic or epigenomic techniques (e.g., NGS, transcriptional profiling, chromatin mapping methods).
• Familiarity with analysis or interpretation of high-throughput sequencing data (e.g., RNA-seq, ChIP-seq, ATAC-seq).

Additional Skills

• Strong communication skills for grant writing and stakeholder engagement.
• Demonstrated ability to collaborate across disciplines, including interactions with clinical partners.
• Leadership capability and commitment to mentoring.