Principal Quantitative Scientist (m/f/d) Full-time

Principal Quantitative Scientist

Roche Diagnostics has built a new strategic area – Roche Information Solutions (RIS) – charged with creating a modern portfolio of decision support software products and generating insights that change the way patients are cared for. Our challenge is to bring together complex diagnostic and treatment data from medical devices and IT systems and intelligently process and present this data to clinicians, researchers, and caregivers to improve research outcomes and patient care by offering a suite of Clinical Decision Support (CDS) solutions. We also work with clinical care solutions that are tailored to be used by the patient directly and empower them with the tools to manage their health.

As a Principal Quantitative Scientist, you will act as a scientific leader for Real-World Data (RWD), driving evidence generation that fundamentally shapes the development and adoption of our digital health, IVD, and medical device products. This is a high-impact, independent role requiring deep expertise and the ability to influence critical business and regulatory decisions. Your work will involve strategically shaping analyses involving diverse data types (including EHR, claims, omics, and digital health data) in close alignment with data scientists and biostatisticians.

Your upcoming mission:

RWD Strategy & Execution (End-to-End Leadership):

• Drive the conceptualization, planning, execution, and reporting of advanced RWD studies using various research and commercial healthcare databases.
• Develop rigorous RWD study protocols and lead complex analyses to support the evidence needs of the IVD, medical device, and digital health portfolio.
• Ensure the design, execution, and presentation of RWE adhere to the highest scientific and methodological standards.

Strategic Influence & Adoption

• Act as a RWD leader, working closely with cross-functional stakeholders such as Product Leads, Medical Affairs, and Clinical Development to ensure RWD projects directly support commercial, market access, and regulatory needs.
• Champion RWD's use to supplement clinical evidence and actively identify opportunities where RWD can serve as the primary evidence mechanism to achieve regulatory and reimbursement objectives.
• Collaborate with external partners (KOLs, academic institutions, healthcare authorities) on study design and foster strong relationships to explore new data assets and analytical methodologies

Expertise & Mentorship:

• Leverage and expand expertise in RWD sources, epidemiology, and state-of-the-art causal inference methodologies.
• Promote innovation by enhancing ways of working (processes, methods, technology) and proactively sharing learnings with peers.
• Mentor junior colleagues and act as an influential subject matter expert to the team.

Essential Skills for your mission:

• You hold a PhD (preferred) OR Master's Degree in a Quantitative science field (e.g. Pharmacoepidemiology, Epidemiology, RWD Biostatistics, Pharmacoeconomics, Health Economic and Outcomes Research)
• And 7+ years of directly related (industry, consulting, or other relevant) experience.
• Proven track record of utilizing RWD to support regulatory submissions.
• Solid expertise in epidemiology and causal inference methodologies is required.
• Strong experience in using diverse RWD sources to generate insights and evidence.
• Experience in the Cardiovascular, Renal, and Metabolic (CVRM) therapeutic area is highly preferred.

Bonus Skills:

• Expertise in RWD & Epidemiology: Proven hands-on experience in designing, implementing, and reporting RWD studies, with specific expertise in epidemiology and a passion for making a difference in healthcare.
• Analytics: Programming experience with R, Python, SQL and/or other quantitative software.
• Strategic & Regulatory Acumen: A solid understanding of regulatory guidelines and an ability to use RWD to influence national and international reimbursement and clinical guidelines.
• Project & People Leadership: Strong project management skills, including the ability to manage scope and delegate. You are a recognized team leader with experience mentoring team members and possess a resilient, can-do attitude.
• Communication & Collaboration: Excellent communication and collaboration skills, including the ability to influence others without formal authority. A professional working proficiency in English is required.
• Problem-Solving & Mindset: A data-savvy, creative, and resilient problem solver with a sense of ownership and attention to detail. You are eager to learn and expand your scientific expertise as a reliable team player and thought partner.

What to expect:

• Ambitious and passionate people building meaningful products for a global audience
• An innovative agile working environment allowing for collaboration with really smart people and knowledge sharing in cross-functional teams
• Loads of benefits (Apple hardware, fitness, public transport, lunch benefit, language classes, professional training budget, chance to join global conferences…)
• Flexible working hours and home office policy, 5 weeks vacation
• An amazing office with a rooftop terrace, fully stocked kitchen and amazing barista coffee machines in the middle of Vienna… oh, and did we mention the best team in the world!

In Austria, we have a legal obligation to disclose the minimum salary according to our collective agreement, which is gross EUR 3,843 – per month for this position. But! Rest assured, we offer amazing competitive compensation packages which take into consideration current market trends, therefore you can expect a higher offer that reflects your experience level.

We are committed to providing a healthy, equal and inclusive working environment for our employees to bring true relief to the patient! We care about family friendly career paths, sustainability, a healthy lifestyle and the flexibility of a modern workplace. We maintain a culture of learning and sharing, as well as open and candid feedback. At every level, there are many opportunities to develop and grow – both professionally and personally.

As a healthcare pioneer committed to transforming the lives of billions of people around the globe, we push boundaries to redefine what is possible. We know that early, accurate diagnosis is essential to maintain health, prevent disease and help advance new, targeted treatments and potential cures for the world's most serious health problems. We have a passion for innovation and a profound commitment to make a lasting impact on society by continuing to improve the standard of care for humankind. Our culture inspires us to create healthcare that is sustainable, efficient and financially viable. Healthcare that is built on people's needs, strong data and clinical insights. Healthcare that saves lives.

Interested? Great. We'd like to hear from you! Just send us your CV in English …. and anything else that you think might impress us.

Roche is an Equal Opportunity Employer.