Principal Research Scientist II Full-time

Cell Culture Development Leader

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.

Purpose:

The Cell Culture Development organization within Operations leads the process development and tech transfer of cell culture processes for clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. In addition, we provide subject matter expertise and experimental support for the manufacture of commercial biologics.

Responsibilities:

• Leads a group of 5+ scientists and engineers with BS/MS and PhDs focused on bioprocess modeling, PAT and advanced bioreactor monitoring and control.
• Leads cell culture process development for monoclonal antibodies, bi-specifics, ADCs, fusion proteins and other molecular formats for early and late-stage clinical assets.
• Leads PPQ enabling cell culture process characterization activities.
• Leads/participates in cross-functional CMC teams and reviews relevant sections of regulatory submissions (e.g. IND, BLA, MAA, etc.).
• Advances technical expertise within the cell culture development field. Tracks emerging trends and technologies within the field through internal and external sources, assesses their relevance to AbbVie and facilitates their internal adoption by effectively communicating their value to the business. Pro-actively advises and shares knowledge with the team, peers and senior management.
• Mentor and enhance staff performance to create a climate of excellence to achieve business and scientific objectives.
• Develops, communicates and implements a vision for development of strategic capabilities.
• Identifies and drives technical innovations that will contribute to future business developments and improvements.

Qualifications:

• Bachelor's Degree in Biology, Biochemistry, Chemical Engineering or related field with 16 years of related work; Master's Degree Science or PharmD with 14 years of related work; PhD in Science or related field with 8 years of related work experience. Exceptional candidates with less experience will be considered.
• Outstanding record of accomplishment in the Biotech and/or Biopharmaceutical field.
• Proven ability to innovate with a history of new or improved product releases.
• Has demonstrated the ability to lead scientists and engineers through urgent situations by developing actionable goals and robust implementation plans.
• Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators.
• Must have a results oriented work ethic and a positive, can-do attitude.
• Excellent written and oral communication skills are expected.

Preferred Qualifications:

• Demonstrated proficiency in bench scale bioreactor, shake flask, and other culture systems for the optimization of cell culture processes.
• Experience with or ability to lead a team with focus on development and application of hybrid, machine learning, mechanistic and other advanced modelling techniques.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

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