Principal Research Scientist II, Analytical Development ( On-site, Waltham MA) Full-time

AbbVie Product Development Science And Technology (Pdst) Analytical Development

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.

Abbvie Product Development Science and Technology (PDS&T) Analytical Development – Waltham is responsible for CMC analytical development activities for antibody drug conjugates (ADCs). We are building a team of highly skilled scientists and technical leaders in ADC development to drive the advancement of targeted cancer therapies to improve patient's lives. The Analytical Development- Waltham team is responsible for late-phase to commercial method development, optimization, validation, advanced characterization, process development support, regulatory authoring, and control strategy for ADCs. The team works cross-functionally with process development, regulatory, and quality within the Abbvie network and with contract manufacturing organization and contract laboratories. The Analytical Development – Waltham team is searching for an analytical lead responsible for optimizing and delivering robust methods, reliable results to support process development, designing and implementing automation technologies for mAbs and ADCs. This role requires a strategic thinker with a strong technical analytical background and the ability to lead an analytical team, manage complex projects, and effectively communicate cross-functionally.

Responsibilities

• • Lead analytical team, translating development objectives into actionable analytical activities.
  • Provide technical expertise to analysts in physiochemical analytical methods such as SEC, CE-SDS and iCIEF.
  • Establish collaborations across the organization to support method optimizations and transfers to PDST analytical teams.
  • Design and implement robust automation technologies to provide efficient data collection and analysis.
  • Manage and prioritize analysis to support multiple ADC programs.
  • Interpret and identify data trends in key analytical release and stability assays.
  • Act as the principal contact for all stakeholders and balance conflicting expectations between PDS&T and Analytical areas.
  • Communicate project strategy, key issues, and risks to relevant teams and escalate risks and facilitate resolution within/across functional areas.

Qualifications

• • PhD in analytical chemistry or related field with 8 years of related experience; Master's Degree with 14 years of related experience
  • Technical expertise in CMC analytical chemistry
  • Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies
  • Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

• This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.