Principal Scientist, Cardiovascular In Vivo Pharmacology Full-time

Working With Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Position Summary

We are seeking a cardiovascular biologist with a track record of using molecular and cellular tools and animal models to understand effects of mutation on cardiac structure and function as well as response to intervention. The successful candidate will be able to apply their knowledge of cardiovascular physiology to identify and validate cardiac/cardiovascular targets, establish pharmacodynamic endpoints in vivo and in vitro to enable drug discovery programs, elucidate structural-functional pathophysiology, and direct ex vivo, microscopic, and/or biochemical characterization/analysis of samples. This is a lab-based role with time spent critically reviewing programs/targets, analyzing data, meeting with key stakeholders and leadership to present results, and serving as a team representative.

Position Responsibilities

In the role as a Principal Scientist within Discovery Cardiovascular, the ideal candidate will:

• Perform in vivo and in vitro/ex vivo studies to define pharmacodynamic/pharmacokinetic relationships and characterize and develop models of disease relevant to programs, as well as response to treatment
• Lead studies to completion, which may include directing the analysis of samples internally or externally through management of CRO activities
• Evaluate programs critically and present findings and recommendations to leadership
• Identify opportunities for protocol improvement and develop new experimental protocols
• Employ technical knowledge and theory to make experimental in-life modifications, when necessary
• Document, critically review, modify experimental approach if necessary, and present experimental data in a timely manner
• Collaborate with cross-functional teams by providing timely and actionable study results
• Provide hands-on training and guidance to develop team members or direct reports
• May be a functional area lead for drug discovery programs independently or with support of leadership
• Contribute to and author reports, abstracts, and publications
• Write protocols for IACUC approval and work with IACUC committees

Experience

Basic Qualifications:

• Bachelor's Degree with 8+ years of academic and/or industry experience
• Or Master's Degree with 6+ years of academic and/or industry experience
• Or Ph.D. or equivalent advanced degree in the Life Sciences with 4+ years of academic and/or industry experience

Preferred Qualifications:

• Ph.D. in Physiology, Pharmacology, Biology, Biochemistry, or a related field with 4+ years of relevant industry experience. PharmD/DVM/MD may be considered with a strong track record of achievement in the basic sciences or drug discovery from hands-on contributions. Alternatively, a M.S. in a related field with 6+ years (after completion of degree) relevant industry experience.
• Strong understanding of cardiovascular physiology and modern cardiovascular methodologies.
• Hands-on experience handling rodents is necessary
• Strong understanding of echocardiography (theory, practice, and interpretation) is preferred with hands-on experience performing echocardiography in rodents strongly preferred.
• Strong understanding of cardiovascular hemodynamics is preferred with hands-on experience performing invasive hemodynamics in rodents strongly preferred.
• An understanding of the considerations for the use of animals in research, with a focus on rationale for species-specific use, can articulate and apply 3Rs principles in designing and initiating experiments
• Highly motivated- driven by achieving goals in a team environment.
• Excellent laboratory skills, prioritizing accurate and reproducible work.
• Excellent organizational and time management skills.
• Must be self-motivated, detail-oriented, collaborative, and able to work effectively in a multidisciplinary, matrixed team environment.

Compensation Overview

Princeton – NJ – US: $135,800 – $164,563

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients' lives through science™ “, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles, the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodations/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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