Principal Scientist, Omics – R&D Data Science & Digital Health – Neuroscience Full-time

Principal Scientist, Omics – R&D Data Science & Digital Health

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Role Summary

Our Neuroscience Data Science & Digital Health (DSDH) team integrates the power of multi-omics, digital health technologies and clinical/real-world evidence (RWE) data to accelerate the delivery of transformational therapies for Neurodegeneration, Neuropsychiatry and Ophthalmology. We drive decision-making and breakthroughs from molecular discovery to clinical trials by partnering along the pipeline to ensure that data science & digital health strategies are embedded in every program.

We are seeking a Principal Scientist, Omics to join our DSDH team focused on Neurodegeneration and/or Neuropsychiatry. In this role, you will drive the precision neuroscience strategy by shaping and leading the execution of projects that bring to bear bioinformatics, artificial intelligence and machine learning as needed to link molecular signatures (genetics, gene expression, proteomics) to disease stage and progression, mechanisms of action, and disease endophenotypes. You will be part of a cross-functional team of data science leaders and partner closely with the Neuroscience Therapeutic Area, Quantitative Sciences, and Discovery Product Development and Supply (DPDS).

This position offers the opportunity to transform how we understand disease biology, identify novel targets, stratify patients, and deliver better outcomes for people living with neurodegenerative and neuropsychiatric disorders.

Key Responsibilities

• Shape the strategy and implement projects for data-driven identification and evaluation of novel therapeutic targets, patient stratification approaches and precision biomarkers from the perspective of omics data, brain biology, and mechanism of action, drawing upon a combination of internal and external resources.
• Work in multi-disciplinary teams, composed of discovery scientists, clinicians, computational biologists and biomarker experts to develop precision neuroscience plans across the Neurodegeneration and Neuropsychiatry portfolio, being forward looking and foreseeing a path to launch.
• Remain current on the constantly evolving landscape of neuroscience, neuropsychiatry, and neurodegeneration, omics, bioinformatics and AI/ML research in search of better strategies for accelerating and prioritizing our portfolio based on biological insights.
• Build strong relationships with internal partners and key academic collaborators, technology providers, and consortia to position the company at the forefront of data-driven neuroscience.

Qualifications

• PhD in neuroscience, computational biology, bioengineering, biostatistics, or a related field is required.
• 3+ years of progressive industry or academic experience in applying data-driven methods in the context of target discovery and validation, translational science and patient stratification is required.
• Extensive background working hands-on deriving insights from high-dimensional molecular data – particularly genetic, RNAseq, proteomics and/or single-cell data is required.
• Proficiency in R, Python, or similar programming languages is required.
• Proven track record of scientific contributions in this field with first author publications in high-impact journals is required.
• Experience translating data into strategies and executable action plans is required.
• Ability to clearly communicate technical work to a diverse audience is required.
• Background and experience working in Neurodegeneration and/or Neuropsychiatry is strongly preferred.
• Experience working with and leading interdisciplinary teams through either people or project leadership is preferred.
• Familiarity with machine learning and innovative AI methodologies is preferred.
• Strong reputation for driving novel solutions to problems and providing strategic advice is preferred.
• Familiarity with clinical development processes is preferred.
• Up to approximately 10% yearly travel is required (International, Domestic)

This position currently has the option to follow a hybrid schedule of 3 days per week working on-site and 2 days per week working remotely (no fully remote option available) and can be located in one of our office locations in either Cambridge, MA, Spring House, PA, or San Diego, CA, United States of America; or Beerse, Antwerp, Belgium, and may require approximately 10% travel domestic and international.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or internal employees contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position in the US is $117,000 to $201,250. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

Employees are eligible for the following time off benefits:

Vacation – up to 120 hours per calendar year

Sick time – up to 40 hours per calendar year

Holiday pay, including Floating Holidays – up to 13 days per calendar year

Work, Personal and Family Time – up to 40 hours per calendar year

Additional information can be found through the link below.