Process Chemistry Scientist

Vertex is seeking a talented individual to join our process chemistry group in Boston, MA. This role will support drug substance development programs at Vertex, performing synthetic organic chemistry in the laboratory at a high level to design and execute syntheses of challenging compounds, troubleshoot a diverse range of chemistry issues and devise corrective solutions, and analyze complex data sets that lead to clear conclusions or recommendations to guide the synthetic decision. In addition, the individual is expected to work both independently and in a matrix team environment.

Key Duties and Responsibilities:

Designs, executes, and interprets synthetic organic experiments with a high degree of reliability, independence, and attention to detail
Proficient in application and utility of a variety of analytical tools (NMR, HPLC, LCMS, Biotage) to monitor and analyze experiments
Generate effective hypotheses to pursue synthesis goals and set new experimental direction
Multitask to execute multiple experiments in an efficient manner
Makes conceptual contributions to development activities and scientific strategies
Develops novel and creative solutions to overcome synthetic and manufacturing obstacles
Employs new principles and technologies to promote progress in the synthesis
Maintains accurate records of experiments and results in a laboratory notebook and authors reports as assigned
Draft, review and submit required documentation pertaining to the development and preparation of drug substances under cGMP environment

Knowledge and Skills:

Familiar with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs
Knowledge in writing and transferring developed technology to outside CROs and working with suppliers to solve chemical issues for compound delivery
Excellent verbal and written communication skills to exchange complex technical/scientific information with others in complex situations and to prepare presentations and reports as required
Ability to interact/communicate with various levels throughout the organization
Perform other duties as assigned

Education and Experience Requirements:

PhD with 0 – 3 years relevant synthetic chemistry experience or
MS with 3+ years relevant synthetic chemistry experience or
BS with 6+ years relevant synthetic chemistry experience

Pay Range: $98,900 – $148,400

Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: On-Site Designated

Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Process Chemistry Scientist Full-time NEW

Vertex