Research Associate Full-time

Research Associate

The Lange laboratory for translational proteomics at The University of British Columbia and BC Children's Hospital investigates innovative approaches to precision medicine for childhood cancer patients. We strive to develop new diagnostic and therapeutic approaches to detect and treat children suffering from cancer earlier, better and with reduced impact on their life. To reach this goal, we use mass spectrometry-based proteomics; biochemistry; cell biology; and molecular biology approaches to study protein function and modification in childhood cancers and develop precision medicine pipelines. We are seeking a highly skilled and passionate Research Associate to join us to build and grow proteomics guided precision oncology.

This is an exciting opportunity to be part of the Canadian Pediatric Cancer Consortium ACCESS that brings together Clinicians, Scientists, Patients and Policymakers across Canada to re-think pediatric cancer research and care from the ground up. The Research Associate will have direct access to top-of-the-line Thermo Astral Zoom and Bruker TimsTOF-ultra mass spectrometers, laser capture microdissection, unique open-flow microfluidic probe systems, the Seer Proteograph deep plasma proteome platform, clinical specimens and diverse patient-derived model systems. The successful applicant will also have the opportunity to supervise graduate and undergraduate students, gain leadership experience in collaborative and interdisciplinary projects and contribute to grant applications.

The Lange Lab is a creative, forward-looking and nimble team of scientists with a goal of decoding the human proteome to find new treatment opportunities for children with cancer. We are seeking self-motivated individuals with a strong ability to lead and work collaboratively, and a desire to learn, innovate and bring their expertise to strengthen our team. Based in Vancouver, surrounded by the West Coast mountains, oceans and city life, we are an international and friendly group with a strong motivation to improve patient care.

We embrace tough challenges and take pride in pushing fundamental research all the way to the clinic – today. Together with our partners, we inform the treatment of childhood cancer patients and pave the way to push proteomics-guided precision oncology to the next level. In our recent research, published in Nature Communications, we evaluated the evolution of proteomes and actionable genome variants and established a strong rationale for starting personalized precision diagnostics immediately at diagnosis.

Located at the BC Children's Hospital Research Institute (BCCHR), the leading pediatric research center in Western Canada, you will be embedded in the highly innovative and interdisciplinary research environment spanning BC Children's Hospital, UBC and BC Cancer. Vancouver repeatedly ranks among the most livable places in the world and combines excellence in research with high quality of life. Excellent opportunities for personal and professional development are available.

The Research Associate would be part of a dynamic team of experimental and computational scientists and part of local and national collaborations. You would have direct access to state-of-the-art cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, mass-spectrometry, next-generation sequencing, flow cytometry, imaging and computing infrastructure. More information on the Lange Laboratory can be found at https://langelab.med.ubc.ca/.

The Lab is part of the Canadian Pediatric Cancer Consortium ACCESS and the PROFYLE precision oncology study where you will interact with interdisciplinary teams. This provides an exceptional opportunity to establish a Canada wide network and reputation and an excellent foundation from which to launch into a diverse palette of careers spanning from research faculty and management to health regulation and policy making.

Duties may include:

• Provide leadership and strategic direction in basic/translational cancer research
• Identify, develop and write grant applications
• Design and conduct cellular biology, proteomics and other cancer biology experiments and data analyses
• Implement and advance new mass spectrometry approaches
• Develop and conduct outreach and knowledge translation activities
• Supervise & mentor team members and collaborators
• Train and support team members in manuscript and grant writing
• Engage with team members and collaborators to make key contributions to experimental design, data visualization & interpretation and overall direction of studies
• Represent the laboratory in national and international initiatives, lead collaborative projects, train graduate and undergraduate students and introduce new methodologies to the lab

Successful applicants will have:

• PhD and postdoctoral fellow training with expertise in cancer biology, proteomics and/or computational biology / machine learning
• A proven track record with first author publication(s) in journals relevant in your field and/or shared as preprints
• Strong statistical foundation and expertise in R or python for data analysis
• Fluent in written and spoken English and demonstrated excellence in scientific writing
• Previous experience in proposal/grant writing is an asset
• Exceptional interpersonal and organizational skills
• Expertise in mechanisms of disease, organelle biology and chromatin organization is an asset
• Expertise in sarcoma, neuroblastoma, CNS malignancies and/or signaling in the tumor microenvironment is an asset
• Hands-on expertise in spatial or single-cell proteomics, cell surface characterization, plasma proteomics, extracellular vesicle or PTM analysis, immunology, microfluidics, imaging and/or histopathology are assets
• Willingness to respect diverse perspectives, including perspectives in conflict with one's own.
• Demonstrates a commitment to enhancing one's own awareness, knowledge, and skills related to equity, diversity, and inclusion.

The expected salary for this full-time position is $70,000 per annum. The Faculty of Medicine is committed to offering equitable and competitive salaries, commensurate with the qualifications and experience of the candidate.

To apply, please submit the following:

• Cover letter expressing your long-term research vision, career goals and fit for the position
• Curriculum vitae
• Copies of your most impactful papers (max 3, submitted or preprint OK)
• Contact information for 3 references

Applications will be reviewed starting February 23, 2026. The desired start date for this position is March 1, 2026 or a date to be mutually agreed.

We invite applications from qualified candidates who share our commitment to employment equity and inclusive excellence, and we welcome applications from candidates belonging to historically, persistently, or systemically marginalized groups: Indigenous (First Nation, Métis, Inuit) Peoples, racialized persons, persons with disabilities, women, 2SLGBTQIA+ people, and trans and non-binary people.

The University is committed to creating and maintaining an inclusive and equitable work environment for all members of its workforce. An inclusive work environment presumes an environment where differences are appreciated, recognized, and integrated into current structures, planning, and decision-making modes. Within this hiring process we are committed to creating an inclusive and equitable process for all candidates (including but not limited to people with disabilities). Confidential accommodations are available on request. If you have any questions regarding accommodations or accessibility during the recruitment and hiring process or for more information and support, please visit UBC's Centre for Workplace Accessibility website at https://hr.ubc.ca/health-and-wellbeing/workplace-accessibility/centre-workplace-accessibility or contact the Centre at workplace.accessibility@ubc.ca.

With gratitude, we acknowledge that the University of British Columbia Faculty of Medicine and its distributed programs, which include four university academic campuses, are located on traditional, ancestral and unceded territories of First Nations Peoples and communities around the province.

Our Vision: To Transform Health for Everyone.

Ranked among the world's top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care professionals, making remarkable discoveries, and helping to create the pathways to better health for our communities at home and around the world.

The Faculty – comprised of approximately 2,200 administrative support, technical/research and management and professional staff, as well approximately 650 full-time academic and over 10,000 clinical faculty members – is composed of 19 academic basic science and/or clinical departments, three schools, and 24 research centres and institutes. Together with its University and Health Authority partners, the Faculty delivers innovative programs and conducts research in the areas of health and life sciences. Faculty, staff and trainees are located at university campuses, clinical academic campuses in hospital settings and other regionally based centres across the province.

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